# Antibody and Bioresource

> **NIH NIH P30** · SLOAN-KETTERING INST CAN RESEARCH · 2020 · $292,922

## Abstract

ABSTRACT
The Antibody and BioResource (ABR) Core is a vibrant facility that contributes broadly to the basic and
translational mission of the Center by focusing on two tools central to reproducibile research, specifically
antibodies and cell lines. The Core works with researchers to develop new monoclonal antibodies (MAbs)
against their target(s) of interest that will work in the required application(s). When antibodies are not readily
available elsewhere, particularly newly developed at MSK, the facility provides access to essential MAbs by: 1)
Producing (in vitro); 2) Purifying; 3) Conjugating (to fluorphores and proteins); and/or 4) Fragmenting them into
Fab or F(Ab’)2 fragments. To promote the use of healthy cell cultures, which is central to generating
reproducable data from these in vitro systems, the ABR Core offers a mycoplasma testing service. Well
authenticated cell lines created at MSK and deposited into the Core are distributed to researchers around the
world, which ensures the tools that the Cancer Center is sharing are of the highest quality. Relevant
information and testing results on curated cell lines are also shared with recipients. These include, but are not
limited to, a description and history of the line, references, culture conditions, unique characteristics, STR
profiles for authentication purposes of human cell lines, images of the cells, confirmation that no mycoplasma
was detectable in the culture, karyotyping, and appropriate flow cytometric analysis. During the past grant
period the ABR Core has contributed to 50 publications for researchers from seven of the 10 CCSG Programs.

## Key facts

- **NIH application ID:** 9858280
- **Project number:** 5P30CA008748-54
- **Recipient organization:** SLOAN-KETTERING INST CAN RESEARCH
- **Principal Investigator:** Frances Weis-Garcia
- **Activity code:** P30 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $292,922
- **Award type:** 5
- **Project period:** — → —

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/9858280

## Citation

> US National Institutes of Health, RePORTER application 9858280, Antibody and Bioresource (5P30CA008748-54). Retrieved via AI Analytics 2026-05-22 from https://api.ai-analytics.org/grant/nih/9858280. Licensed CC0.

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