# Arkansas Center for Food Allergy Research (ArCOFAR)

> **NIH NIH UM1** · ARKANSAS CHILDREN'S HOSPITAL RES INST · 2020 · $235,000

## Abstract

PROJECT SUMMARY
Food allergy is a disease of global impact associated with life-threatening reactions, increasing prevalence,
and limited options for treatment and prevention. Despite significant research advances, many remaining
questions must be addressed before global implementation of impactful therapeutic and prevention options for
patients affected by food allergy can be realized. The Consortium for Food Allergy Research (CoFAR) was
formed to address these unresolved questions through its collaborative research network of Clinical Research
Units (CRU) with experience and expertise in food allergy clinical trials. To this end, the Arkansas Center for
Food Allergy Research (ArCOFAR) builds on a >30 year foundation of excellence, expertise, and leadership
in food allergy and is prepared to immediately address the overarching program goals of CoFAR. The
ArCOFAR site is ideally-positioned to function as a CoFAR CRU through contribution of our extensive research
experience and by capitalizing on our population's unique geographic and patient demographic characteristics.
Our efforts will be directed by the central hypothesis that ArCOFAR will enable the participation of diverse
groups of food allergic individuals in expertly designed, innovative clinical trials of the highest quality
and scientific value. Our overarching goal is to provide a unique research platform to measurably improve
the lives of children and adults with food allergy. This goal will be accomplished by the design and
implementation of innovative clinical studies and therapeutic trials via high-quality, high-impact research
collaboration. Our hypothesis will be tested by executing four specific aims: 1) Leverage established expertise
in food allergy research as a platform to expand clinical trials development in immunotherapeutics through
integrated research efforts with other CoFAR CRUs; 2) Apply institutional and community resources to expand
ArCOFAR CRU capacity for population-based research in food allergy, including participation in birth cohort
and longitudinal outcome studies; 3) Link current inter- and intra-institutional resources to broaden the scope of
clinical research participation to include a more diverse population of food allergic patients; 4) Promote career
development of new and early career food allergy researchers through active recruiting and mentoring of new
faculty and linking established programmatic and network resources. In addition, our cutting-edge clinical trial
of walnut oral immunotherapy will address an unmet need in management of tree nut allergy. Further,
ArCOFAR's multi-disciplinary team with established expertise and international leadership in food allergy
clinical trials, will expand clinical research through the development and testing of novel immunotherapeutics
and implementation of cohort studies, while providing mentoring and career development opportunities to early
and new career investigators. The outcome of this proposal will be to...

## Key facts

- **NIH application ID:** 9864000
- **Project number:** 5UM1AI130781-04
- **Recipient organization:** ARKANSAS CHILDREN'S HOSPITAL RES INST
- **Principal Investigator:** Stacie M Jones
- **Activity code:** UM1 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $235,000
- **Award type:** 5
- **Project period:** 2017-03-03 → 2024-02-29

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/9864000

## Citation

> US National Institutes of Health, RePORTER application 9864000, Arkansas Center for Food Allergy Research (ArCOFAR) (5UM1AI130781-04). Retrieved via AI Analytics 2026-05-22 from https://api.ai-analytics.org/grant/nih/9864000. Licensed CC0.

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