# Methods Core

> **NIH NIH P30** · UNIVERSITY OF CALIFORNIA LOS ANGELES · 2020 · $364,788

## Abstract

ABSTRACT
 The Methods Core provides expertise, leadership and infrastructure to promote and facilitate the quality of
HIV research conducted by CHIPTS researchers and collaborators, both domestically and globally. The
Methods Core has a history of venturing to the cutting edge of research methodology and technology to offer
the HIV research community new platforms and tools to optimize the potential of their research. This includes
integrating mobile phone-based assessment, biomarker data, and other measurement techniques into study
designs that maintain scientific rigor while adapting to the evolving environment of HIV prevention research.
Consistent with OAR's NIH HIV/AIDS funding priorities, the Methods Core will provide services to guide
research linked to HIV, with specific focus on comorbidities of substance use and mental health disorders that
interfere with consistent viral suppression in HIV-positive individuals and in sustaining optimal prophylaxis for
high-risk individuals. The Methods Core recognizes the paradigm shift required beyond traditional analytic
approaches to incorporate advanced analytical approaches, and to broaden involvement across different
disciplines, such as medicine, HIV, mental health and drug abuse research fields. As well, the interplay of
technology and implementation science requires method development to advise HIV intervention delivery in
real-world settings. Its three specific aims are: (1) SCIENCE: To foster cutting edge research by developing
and disseminating innovative technologies and analytic strategies (e.g., modern measurement tools and
multivariate statistical techniques) to HIV treatment and prevention research; (2) NETWORKING: To connect
scientists across disciplines and with community partners to understand the available analytic methodologies
and linking scientists to partners with complementary expertise; and (3) CAPACITY BUILDING: To recruit,
mentor, retain high caliber investigators with methods expertise and to disseminate innovative methods, tools,
and platforms through seminars and webinars. The Methods Core is a backbone for both CHIPTS scientists
and community partners and prioritizes three overlapping areas of focus when providing services:
measurement, statistical methods and multivariate models, and implementation science. The Methods Core is
led by Director Li Li, PhD, Co-Director W Scott Comulada, DrPH, and Associate Director Sung Jae-Lee, PhD.
The types of services provided include consultations on research design, power and sample-size calculations,
data analysis, data management, grant proposal development, preparation of research findings for publication,
training workshops and seminars and selection of appropriate models, including analysis of multiple biomedical
and behavioral HIV end points. Epidemiological and biostatistical expertise within a broader causal-inference
paradigm have always been central to guiding services provided by the Methods Core.

## Key facts

- **NIH application ID:** 9864091
- **Project number:** 5P30MH058107-24
- **Recipient organization:** UNIVERSITY OF CALIFORNIA LOS ANGELES
- **Principal Investigator:** Li Li
- **Activity code:** P30 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $364,788
- **Award type:** 5
- **Project period:** — → —

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/9864091

## Citation

> US National Institutes of Health, RePORTER application 9864091, Methods Core (5P30MH058107-24). Retrieved via AI Analytics 2026-05-21 from https://api.ai-analytics.org/grant/nih/9864091. Licensed CC0.

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