# Combination Prevention Core

> **NIH NIH P30** · UNIVERSITY OF CALIFORNIA LOS ANGELES · 2020 · $230,625

## Abstract

ABSTRACT
 The CHIPTS Combination Prevention (CP) Core promotes development and evaluation of interventions that
integrate evidence-based behavioral, biomedical, technological and structural components to reduce HIV
incidence and to optimize each step of the HIV care and prevention continua. In response to strategic planning
and anticipation of the medicalization of HIV prevention, the CP Core focuses its resources on guiding efforts
that address persistent gaps in access and adherence to care and prevention in key populations, including men
who have sex with men of color, African American women, transgender individuals, youth, homeless, and
incarcerated individuals. Within these key populations, we further target those with comorbidities of substance
use and mental health disorders and other factors that interfere with access and adherence to antiretroviral
therapy (ART). While efforts to produce measurable outcomes (e.g., viral suppression, reduction in incidence)
to HIV prevention have shown remarkable success using ART, the research was conducted on populations
compliant with medications. Yet the disorganizing effects in key populations of comorbid substance use and
mental health disorders contribute to “leaks” in the HIV prevention and care continua. Its three specific aims are:
(1) SCIENCE: To lead the science agenda on combining behavioral, biomedical, technological and structural
interventions to optimize HIV care and HIV prevention outcomes, with a focus on those with mental health and/or
substance use disorders, domestically and globally; to lead in scientific research networks (e.g., HPTN, ACTG);
(2) NETWORKING: To convene activities that present best practices for dissemination and scale-up of
behavioral, biomedical, technological, and structural interventions; to promote science development by engaging
investigators and community stakeholders; (3) CAPACITY BUILDING: To build capacity within affected
communities, key stakeholders, and service organizations through community education and workforce training;
to mentor emerging scientists and faculty on combination prevention approaches; to facilitate linkages between
community members interested in HIV therapeutic or prevention research with ongoing research opportunities.
This coordinated agenda of science, networking and capacity building will generate vanguard information and
expertise that will guide efforts towards HIV eradication in both the general population and in key populations.
The CP Core team is led by Director Cathy Reback, PhD, Co-Director Raphael Landovitz MD, MSc, and
Associate Director Danielle Harris, MPH. Core services include: advise on research on combination HIV
prevention; provide guidance on study of substance use and mental health in the context of HIV prevention;
provide peer review; translate domestic HIV prevention strategies for use in foreign settings and back; advise
and train cultural competence, especially in key populations with comorbid conditions; c...

## Key facts

- **NIH application ID:** 9864093
- **Project number:** 5P30MH058107-24
- **Recipient organization:** UNIVERSITY OF CALIFORNIA LOS ANGELES
- **Principal Investigator:** Cathy J Reback
- **Activity code:** P30 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $230,625
- **Award type:** 5
- **Project period:** — → —

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/9864093

## Citation

> US National Institutes of Health, RePORTER application 9864093, Combination Prevention Core (5P30MH058107-24). Retrieved via AI Analytics 2026-05-21 from https://api.ai-analytics.org/grant/nih/9864093. Licensed CC0.

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