# Core F: Biostatistics and data management core

> **NIH NIH P30** · UNIVERSITY OF PENNSYLVANIA · 2020 · $221,721

## Abstract

CORE F Abstract/Summary
The Biostatistics and Data Management Core (Core F) was established in recognition of the critical need for
statistical and data management expertise in the design, implementation, and analysis of clinical and basic
research related to mental health in HIV/AIDS. The Core provides the Penn Mental Health AIDS Research
Center (PMHARC) pilot investigators with collaboration for planning and execution of exploratory
investigations, proposal development, and guidance on quantitative and qualitative data management and
analyses. The overall mission of Core F is to encourage and facilitate high quality innovative, interdisciplinary
and translational mental health in HIV/AIDS research in the PMHARC. The Core promotes the use of rigorous
statistical and analytic methodologies and effective data management by working across the Core boundaries.
The Core's specific aims will be to: 1) advise and collaborate with PMHARC investigators on study design,
data management, and data analysis, including qualitative research and mixed methods approaches; 2)
evaluate feasibility of intervention studies and facilitate conduct of precursor pilot studies; 3) collaborate on the
design, implementation, data management and analysis for four to six pilot studies per year; 4) maintain and
expand the central database of the PMHARC's core set of clinical assessments and biomarkers related to HIV,
mental illness, and co-morbidities collected from pilot studies and facilitate future research involving the use of
the PMHARC pooled database; and 5): provide statistical collaboration for research funding applications (e.g.
R01, R21, R34). Many projects can be completed with the use of standard statistical methods, but in some
cases it is necessary to either adapt existing methods or develop new ones in order to achieve a satisfactory
analysis. Mental health data carries with it substantial structural burdens that tax standard statistical
methodology, issues of inference, and issues of appropriate design. These burdens include nonadherence to
treatment, missing data, correlated data over time, and correlation among various outcome measures. Thus
Core F is equipped to deal with interesting but complex issues that might not present themselves in other
environments (e.g. CFAR). It is expected that as individual R01s are awarded that faculty, the Biostatistics
Analysis Center (BAC), and the Mixed Methods Research Lab (MMRL) will be part of the research team as
appropriate to size and complexity of study. In general, the Core's model will be to utilize personnel effort for
pilot projects and preparation of funding proposals, with the subsequent funded grants providing direct support
of the resulting collaborative research effort. Methodological work will also be financed by PMHARC core
funding as well as from outside funding generated from external awarded grants.

## Key facts

- **NIH application ID:** 9864100
- **Project number:** 5P30MH097488-08
- **Recipient organization:** UNIVERSITY OF PENNSYLVANIA
- **Principal Investigator:** Knashawn Hodge Morales
- **Activity code:** P30 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $221,721
- **Award type:** 5
- **Project period:** — → —

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/9864100

## Citation

> US National Institutes of Health, RePORTER application 9864100, Core F: Biostatistics and data management core (5P30MH097488-08). Retrieved via AI Analytics 2026-05-21 from https://api.ai-analytics.org/grant/nih/9864100. Licensed CC0.

---

*[NIH grants dataset](/datasets/nih-grants) · CC0 1.0*