# Methodology Core

> **NIH NIH U54** · WASHINGTON STATE UNIVERSITY · 2020 · $114,259

## Abstract

METHODLOGY CORE 
Abstract 
The initiatives of Healthy People 2020 place a high priority on research and federal policy to eliminate racial and 
ethnic disparities in health status, health behaviors, functional limitations, and healthcare use. Yet, American 
Indians (AI), Alaska Natives (AN), and Native Hawaiian and Pacific Islanders (NHPI) suffer a disproportionate 
burden of hypertension, its attendant CVD and stroke risk factors, as well as clinical CVD and stroke, compared 
to other US populations. The Native-Controlling Hypertension And Risks through Technology (Native-CHART) 
Methodology Core is devoted to optimizing blood pressure intervention research with partners that serve these 
populations. Its goals are to make efficient use of study resources, to optimize internal and external study validity, 
and to improve inferential ability. Core members will be involved in study design, sample selection, 
measurement, data collection, data management, data analysis, and dissemination of findings. We integrate 
methods from epidemiology, biostatistics, health economics, health services and policy, and health outcomes 
research, augmented with exceptional experience in qualitative methods. Our Specific Aims are to: 1) 
collaborate with our community partners and the Consortium Core to develop and implement methods for 
collecting data for the baseline and subsequent needs assessments; 2) apply state-of-the-art research designs, 
sampling strategies, and analysis techniques to test the impact of novel interventions for the reduction of blood 
pressure and its attendant CVD and stroke risk factors among AI, AN, and NHPI people with hypertension. This 
includes locating each Intervention Project within a theoretical framework that reflects the interdependent nature 
of multilevel interventions; ensuring the reliability and validity of measures, with attention to minimizing 
measurement error and best practices for data collection; and applying a flexible and comprehensive data 
analysis strategy guided by multilevel models. This strategy encompasses longitudinal data structures including 
within-person change, group-randomized trials, and cross-level intervention effects, using random effects 
estimation, generalized estimating equations, and others; maximizing efficient use of resources in developing 
policies and procedures; manualizing operations; designing questionnaires and data collection; managing data 
and statistical analyses; disseminating findings; and integrating qualitative and quantitative methods to 
contextualize and enhance the cultural relevance and public health impact of the Projects; and 3) perform 
systematic economic evaluations of the hypertension-control programs through cost-benefit and cost- 
effectiveness analyses. Our long history of collaboration with the Intervention Project Leaders and Satellite 
Center Directors is complemented by the Methodology Core’s understanding of the unique needs and challenges 
inherent in co...

## Key facts

- **NIH application ID:** 9868828
- **Project number:** 5U54MD011240-05
- **Recipient organization:** WASHINGTON STATE UNIVERSITY
- **Principal Investigator:** STEPHEN M SCHWARTZ
- **Activity code:** U54 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $114,259
- **Award type:** 5
- **Project period:** — → 2022-06-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/9868828

## Citation

> US National Institutes of Health, RePORTER application 9868828, Methodology Core (5U54MD011240-05). Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/grant/nih/9868828. Licensed CC0.

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