# Tissue Core

> **NIH NIH P30** · H. LEE MOFFITT CANCER CTR & RES INST · 2020 · $188,796

## Abstract

PROJECT SUMMARY 
The Tissue Core (TC) serves as the central biorepository for Moffitt Cancer Center (MCC). Opened in 1992, the 
overall goal of the TC is to collect, process, store, and release high-quality, well-annotated biospecimens in support 
of basic, population, clinical, and translational research. TC biobanking activities at MCC have three foremost 
specific aims: 
1. Serve as a centralized MCC biobanking resource for the collection, processing, and storage of human 
 biospecimens in support of member science; 
2. Implement biorepository best practices and quality metrics that ensure members' access to high quality 
biospecimens; 
3. Develop and promote policies, guidelines, and procedures that facilitate members' efficient access to human 
 biospecimens in a regulatory-compliant manner. 
The TC is housed in a 2,800 square foot facility and staffed by 20 highly trained Biorepository Specialists, Staff 
Scientists, a Research Pathologist, and a Manager that collectively support investigator-driven studies and the 
general banking operations. TC services are housed within three distinct sections: Intake & Acquisition, Sample 
Processing Lab, and Research Histology Services. Collectively, the three sections provided support for 206 
protocols during fiscal year 2015 (FY15). The TC provides a wide variety of services such as collection of fresh 
frozen tissue, general histology, immunohistochemistry, nucleic acid extraction, construction of tissue microarrays 
(TMA), and release of archived biospecimens. Moreover, in support of investigator-driven studies, the TC 
incorporates specific needs and applications into project-specific SOPs, which often include contributing to the 
study design and collection strategies to optimize biospecimen handling. Overall, the TC offers 81 distinct 
biobanking and biospecimen-related services that meet or exceed NCI best practice recommendations and College 
of American Pathologists (CAP) Biorepository Accreditation standards to ensure high-quality biospecimen 
collection and processing validated through standardization, documentation, and emphasis on quality 
management. In addition to contributing to 173 publications during the past five years, the TC's high-quality 
biobanking infrastructure was instrumental in MCC's successful Lung SPORE, Skin SPORE, BMaP-3, TCGA, and 
CPTAC submissions. During the prior period, the TC provided significant support to members, demonstrated by a 
yearly average of nearly 73,000 service units, with FY15 representing a record year of usage with 85,708 service 
units. In FY15, TC services were utilized by 86 members distributed across all five CCSG programs, with 78% of 
total usage by peer-review-funded members.

## Key facts

- **NIH application ID:** 9868922
- **Project number:** 5P30CA076292-22
- **Recipient organization:** H. LEE MOFFITT CANCER CTR & RES INST
- **Principal Investigator:** Conor C Lynch
- **Activity code:** P30 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $188,796
- **Award type:** 5
- **Project period:** — → —

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/9868922

## Citation

> US National Institutes of Health, RePORTER application 9868922, Tissue Core (5P30CA076292-22). Retrieved via AI Analytics 2026-05-23 from https://api.ai-analytics.org/grant/nih/9868922. Licensed CC0.

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