# Center for the Study of Complex Malaria in India

> **NIH NIH U19** · NEW YORK UNIVERSITY · 2020 · $543,541

## Abstract

PROJECT 2 SUMMARY
In this project, we address key gaps in our knowledge of P. vivax hypnozoite biology through screening relapse
patients for serological markers associated with the carriage of hypnozoites. We also plan to develop the
Oxford Nanopore Technologies MinION genomics platform for use at our field sites in India. Finally, we will
continue our development of a P. vivax haplotype map to identify India-specific selective sweeps and hot-
spots, and sequence the genomes of P. vivax parasites from relapse patients. Our focus on P. vivax biology in
this project is concordant with the recent announcement of an Indian National Framework for Malaria
Elimination, which outlines a “Special strategy for P. vivax elimination” since “more than 80% of the global P.
vivax burden is contributed by 3 countries including India”.

## Key facts

- **NIH application ID:** 9869841
- **Project number:** 5U19AI089676-11
- **Recipient organization:** NEW YORK UNIVERSITY
- **Principal Investigator:** JANE M CARLTON
- **Activity code:** U19 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $543,541
- **Award type:** 5
- **Project period:** — → —

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/9869841

## Citation

> US National Institutes of Health, RePORTER application 9869841, Center for the Study of Complex Malaria in India (5U19AI089676-11). Retrieved via AI Analytics 2026-05-22 from https://api.ai-analytics.org/grant/nih/9869841. Licensed CC0.

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