# Predicting Educational Success in Autism from Social Neuroscience in Infancy: A Longitudinal Investigation from Birth Until 3rd Grade

> **NIH NIH K99** · EMORY UNIVERSITY · 2020 · $100,901

## Abstract

PROJECT SUMMARY/ABSTRACT
 The goal of this Pathway to Independence Award (K99/R00) is to promote an independent research career
by complementing the candidate’s training in neuroscience and education with expert mentorship in the
measurement and analysis of social visual engagement (SVE), clinical monitoring of early typical and atypical
social communication development, and novel statistical methods for longitudinal data analysis. The
candidate’s short-term goal is to identify robust, early clinical and SVE predictors of functional communication
skills, kindergarten readiness, and literacy outcomes in children with autism spectrum disorder (ASD) and
related communication disorders (CDs). SVE measures—collected via eye-tracking technology—quantify the
way in which children visually explore, engage with, ultimately learn from, and adapt to their surrounding world
at different stages of life, and may provide key insights into atypical versus typical developmental processes
over the early lifespan. The proposed project will capitalize on an established longitudinal cohort of 268 ASD,
CD, and typically developing children who have, to date, contributed more than 8,000 clinical and 2,300 SVE
measures over 12 time points from birth to age 3. The candidate will collect follow-up SVE, kindergarten
readiness, and literacy development measures on this sample, when children are 5 (kindergarten), 6 (1st
grade), 7 (2nd grade), and 8 (3rd grade) years of age. Longitudinal trajectories of clinical assessment measures
will be tested for prediction of functional communication outcomes at age 3, kindergarten readiness outcomes
at age 5, and literacy development at ages 5, 6, 7, and 8. Patterns and trajectories of SVE will also be
investigated for their association with these developmental outcome measures. The candidate will directly test
the extent to which specific inputs, timing, and dosage (i.e., magnitude and rate) of developmental divergences
in trajectories relate to outcome. This work will provide quantitative, objective, community-viable, performance-
based biomarkers for predicting and monitoring risk of school difficulties, and enable the identification of
actionable targets and developmental windows of opportunity for early intervention in children with ASD and
CDs. The training plan is supported by a multidisciplinary team of mentors—including Drs. Ami Klin, Warren
Jones, Lindee Morgan, and Amy Wetherby—and the strengths of the Marcus Autism Center, one of only five
NIH Autism Centers of Excellence, providing groundbreaking research and clinical care for individuals with
ASD. The intersection of these strengths provides an ideal training environment for promoting the candidate’s
transition to independent investigator, and leading a research program that leverages tools and insights from
social neuroscience to improve early and school-based educational interventions for children with ASD and
CDs.

## Key facts

- **NIH application ID:** 9878901
- **Project number:** 5K99HD097290-02
- **Recipient organization:** EMORY UNIVERSITY
- **Principal Investigator:** Laura Edwards
- **Activity code:** K99 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $100,901
- **Award type:** 5
- **Project period:** 2019-03-01 → 2021-04-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/9878901

## Citation

> US National Institutes of Health, RePORTER application 9878901, Predicting Educational Success in Autism from Social Neuroscience in Infancy: A Longitudinal Investigation from Birth Until 3rd Grade (5K99HD097290-02). Retrieved via AI Analytics 2026-05-23 from https://api.ai-analytics.org/grant/nih/9878901. Licensed CC0.

---

*[NIH grants dataset](/datasets/nih-grants) · CC0 1.0*
