# COBRE Center for Neuromodulation (CCN)

> **NIH NIH P20** · BUTLER HOSPITAL (PROVIDENCE, RI) · 2020 · $2,040,123

## Abstract

PROJECT SUMMARY
The COBRE Center for Neuromodulation (CCN) will be centered at Butler Hospital, a freestanding psychiatric
and neuropsychiatric hospital affiliated with the Alpert Medical School at Brown University. This COBRE will
create key infrastructure and support a core group of interdisciplinary investigators to build a self-sustaining
center of excellence in clinical-translational brain research. Its overall goal is to advance the use of noninvasive
neuromodulation in circuit-based therapies for neuropsychiatric disorders.
This application brings together three highly promising junior investigators, who will use methods of
noninvasive brain stimulation (transcranial magnetic and transcranial electrical stimulation) and neuroimaging
tools (structural and functional MRI). They will work together on clinical-translational research on brain circuits
relating to symptoms and dimensions of illness. Their areas of interest are impulsive behavior, PTSD, and
obsessive-compulsive disorder (OCD). Using experienced, highly skilled mentors working within the structure
of an Administrative Core, the CCN will advance the careers of these talented young researchers towards the
next level of research independence.
The CCN will support two new research cores: the Design and Analysis Core (DAC) and the Neuroimaging
and Neuromodulation Core (NNC) at Butler Hospital. These cores will provide essential infrastructure needed
to successfully carry out each project. This includes statistical and methodological consultation and expertise
needed to design and analyze the studies proposed (DAC), and equipment, technical support, and expertise
necessary for stimulation implementation and acquisition of neuroimaging data (NNC).
The Administrative Core will also support pilot grants relating to our theme of translational research in neural
circuits and disease. These grants will be awarded yearly in years 2 to 5 of the Center.
The CCN will establish Butler Hospital as a national leader in this exciting field of translational medicine, which
will expand research and clinical application of noninvasive brain stimulation across disorders of brain and
behavior. It will unify an interdisciplinary community in clinical-translational research of neuropsychiatric illness,
for the ultimate benefit of patients.

## Key facts

- **NIH application ID:** 9882291
- **Project number:** 5P20GM130452-02
- **Recipient organization:** BUTLER HOSPITAL (PROVIDENCE, RI)
- **Principal Investigator:** BENJAMIN D GREENBERG
- **Activity code:** P20 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $2,040,123
- **Award type:** 5
- **Project period:** 2019-03-01 → 2024-01-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/9882291

## Citation

> US National Institutes of Health, RePORTER application 9882291, COBRE Center for Neuromodulation (CCN) (5P20GM130452-02). Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/grant/nih/9882291. Licensed CC0.

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