# COBRE in CV Health Research Core

> **NIH NIH P20** · UNIVERSITY OF DELAWARE · 2020 · $245,841

## Abstract

PROJECT SUMMARY/ABSTRACT
The COBRE in Cardiovascular Health brings together investigators from multiple disciplines focused on
vascular aspects of cardiovascular health and will establish a new Cardiovascular Research Core at the
University of Delaware (UD). The COBRE in Cardiovascular Health will capitalize on an emerging strength in
cardiovascular research at UD creating a new signature COBRE, and researchers from multiple disciplines in
the center will investigate the mechanisms, consequences, and potential interventions for declining
cardiovascular health spanning basic, clinical/translational, and community based research to a degree that
cannot be supported by existing instrumentation. Thus, this center will establish a Cardiovascular Research
Core and support the established Delaware Biotechnology Institute (DBI) Bio-Imaging Core. These cores will
provide resources for assessment of cardiovascular function and health, biostatistics, and bioimaging that will
enhance cardiovascular research capabilities of the subproject investigators, as well other investigators in the
center, university, and region.
This establishment of a Cardiovascular Research Core (CVRC) will facilitate the assessment of cardiovascular
function in rodents and humans. The CVRC will enable researchers to assess vascular function in rodents and
humans, and ambulatory and central blood pressure in humans through the availability of instrumentation and
personnel expertise. This core takes advantage of new facilities in the UD Health Sciences Complex and
collaboration with the UD Nurse Managed Health Center. A plan for the establishment, oversight and
maintenance of the CVRC is outlined.
We will also support and expand existing DBI Bio-Imaging Core to facilitate the imaging of endothelial cells
collected from human volunteers as well as vessels from rodent bone. We will expand the existing Bio-Imaging
Center with the addition of a microscope slide scanner and imager for high throughput imaging of slides and
provide support for Bio-Imaging personnel. A plan for oversight and maintenance is outlined.

## Key facts

- **NIH application ID:** 9883020
- **Project number:** 5P20GM113125-05
- **Recipient organization:** UNIVERSITY OF DELAWARE
- **Principal Investigator:** DAVID G EDWARDS
- **Activity code:** P20 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $245,841
- **Award type:** 5
- **Project period:** — → 2021-08-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/9883020

## Citation

> US National Institutes of Health, RePORTER application 9883020, COBRE in CV Health Research Core (5P20GM113125-05). Retrieved via AI Analytics 2026-05-26 from https://api.ai-analytics.org/grant/nih/9883020. Licensed CC0.

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