# Core C: Animal Models Core

> **NIH NIH P01** · VERSITI BLOOD HEALTH, INC. · 2020 · $168,430

## Abstract

PROJECT SUMMARY: CORE C
The Animal Model Core will support the generation of genetically modified mouse and rat models for the in vivo
analysis of newly discovered variants of VWF. The Core will function in consultation with the PPG Investigators
to develop the appropriate experimental design and methods to generate these animal models, produce and
validate the required experimental reagents, utilize the existing facilities and technical expertise of the joint
Transgenic Core Facility of the Blood Research Institute (BRI) and the Medical College of Wisconsin (MCW) to
produce the desired animal, and manage the distribution of the genetically altered mice or rats to PPG
Investigators and the wider research community.

## Key facts

- **NIH application ID:** 9891089
- **Project number:** 5P01HL144457-02
- **Recipient organization:** VERSITI BLOOD HEALTH, INC.
- **Principal Investigator:** Hartmut Karl-Heinz Weiler
- **Activity code:** P01 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $168,430
- **Award type:** 5
- **Project period:** — → —

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/9891089

## Citation

> US National Institutes of Health, RePORTER application 9891089, Core C: Animal Models Core (5P01HL144457-02). Retrieved via AI Analytics 2026-05-23 from https://api.ai-analytics.org/grant/nih/9891089. Licensed CC0.

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