# Human Imaging Shared Facility

> **NIH NIH P30** · UNIVERSITY OF ALABAMA AT BIRMINGHAM · 2020 · $218,481

## Abstract

IMAGING GROUP 
HUMAN IMAGING SHARED FACILITY (HISF) 
ABSTRACT 
The Human Imaging Shared Facility (HISF) enhances imaging-related research activities included in the UAB- 
CCC's collaborative group portfolio and other clinical trials through the provision of a standardized approach for 
reviews of each UAB-CCC protocol and coordination of non-routine imaging services. The protocol review is 
performed by two research imaging coordinators who provide quotes for routine and nonroutine research 
imaging services in compliance with institutional and national regulations. Other HISF services include image 
data transfers and protocol specific imaging techniques, phantom scan/site qualification imaging, physicist, 
radiologist, or radiology technologist time, and procurement of information for image data forms. Image data 
transfers meet all UAB Health System Information Security (HSIS) requirements and are audited periodically 
by the UAB HSIS. Accurate and timely analysis of conventional imaging studies used for response assessment 
in cancer clinical trials makes up the bulk of services provided to members of the UAB-CCC. With dedicated 
subspecialty faculty radiologist interpretations coordinated by the assistance of the two radiology research 
imaging coordinators and a metrics coordinator, protocol-specific metrics are generated by the same set of 
designated readers throughout the course of each therapeutic trial for consistent longitudinal metrics reporting. 
In cases of adjudication, the HISF Director works with the PIs and coordinators to resolve reporting issues. 
The HISF promotes the development and incorporation of novel response evaluation methods (imaging 
biomarkers) for cancer preclinical, translational, and Phase I-III clinical trials. Through scientific collaboration 
the HISF can facilitate the translation of more sophisticated imaging examinations, image analytics, and 
metrics utilized by the other imaging cores such as the Preclinical Imaging Shared Facility and Comprehensive 
Core for Quantitative Imaging Biomarker Analysis and Development. These non-standard advanced image 
analyses include physiologic MRI (diffusion weighted imaging, dynamic contrast MRI, MR Spectroscopy), 
investigational PET CT, PET MRI, and Spectral (dual energy) MDCT. Both standard metrics and advanced 
imaging methods will aid investigators in UAB-CCC programs.

## Key facts

- **NIH application ID:** 9895650
- **Project number:** 5P30CA013148-48
- **Recipient organization:** UNIVERSITY OF ALABAMA AT BIRMINGHAM
- **Principal Investigator:** Andrew Dennis Smith
- **Activity code:** P30 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $218,481
- **Award type:** 5
- **Project period:** — → 2022-03-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/9895650

## Citation

> US National Institutes of Health, RePORTER application 9895650, Human Imaging Shared Facility (5P30CA013148-48). Retrieved via AI Analytics 2026-05-23 from https://api.ai-analytics.org/grant/nih/9895650. Licensed CC0.

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