# 04 Neuro-Oncology Program

> **NIH NIH P30** · UNIVERSITY OF ALABAMA AT BIRMINGHAM · 2020 · $119,191

## Abstract

04 NEURO-ONCOLOGY (NO) PROGRAM 
ABSTRACT 
The Neuro-Oncology Program (04) has been a multidsciplinary, vertically integrated, basic, translational and 
clinical research program in the Comprehensive Cancer Center (CCC) since 1986. Its primary cancer focus 
includes molecular, cellular and systems biology of malignant glial tumors with a secondary emphasis on 
metastatic tumors to the brain and on malignant peripheral neuroglial tumors. The Neuro-Oncology Program 
membership has a strong presence in the UAB Comprehensive Neuroscience Center. The CCC Neuro- 
Oncology program serves a 5-state, Deep South region as a major, tertiary care referral center for patients with 
malignant and benign brain tumors and achieves its objectives through the support of the CCC and its shared 
facilities. The Neuro-Oncology Program is distinguished by: 1) A large number of patients with primary brain 
tumors and a mature 5-state referral network; 2) An active brain tumor-dedicated inter-disciplinary clinical 
team; 3) Extensive clinical and laboratory resources; 4) Significant extramural support for basic, translational, 
and clinical research, as well as a number of pharmaceutical industry-academia contracts for support of Neuro- 
Oncology research on campus; and 5) Nationally recognized expertise in conducting institutional and 
cooperative Phase I and II clinical trials utilizing agents developed through translational activities of the 
program. This program is a charter member of the Adult Brain Tumor Consortium (ABTC), the only NCI-funded 
adult brain tumor clinical consortium, and program members hold leadership positions in the Pediatric Brain 
Tumor Committee of the Children's Oncology Group. The Neuro-Oncology Program is multi-disciplinary with 
20 primary members from 9 departments and 2 schools. Our members currently hold 28 active research 
grants, totaling $6,990,899 in direct costs annually, with 10 of those grants from the NCI totaling $680,818 
annually in direct costs. During the current funding period, the membership published 169 peer-reviewed 
scientific papers, of which 32% were intra-programmatic and 29% were inter-progammatic brain tumor 
research. We conducted 66 interventional and 7 non-interventional IRB-approved clinical trials accruing 221 
patients and 366 patients, respectively. In the current funding period, the Program has effectively harnesssed 
the CCC development of infrastructure and expertise to support systems biomedicine, bioenergetics, imaging 
and drug development. This has led to highly innovative research that has resulted in several seminal 
publications by the members of this program. The Neuro-Oncology Program will continue to advance basic 
and translational findings of its members' research to investigator-initiated Phase I and Phase II clinical trials 
for adult and pediatric patients with brain tumors.

## Key facts

- **NIH application ID:** 9895663
- **Project number:** 5P30CA013148-48
- **Recipient organization:** UNIVERSITY OF ALABAMA AT BIRMINGHAM
- **Principal Investigator:** Louis B Nabors
- **Activity code:** P30 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $119,191
- **Award type:** 5
- **Project period:** — → 2022-03-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/9895663

## Citation

> US National Institutes of Health, RePORTER application 9895663, 04 Neuro-Oncology Program (5P30CA013148-48). Retrieved via AI Analytics 2026-05-22 from https://api.ai-analytics.org/grant/nih/9895663. Licensed CC0.

---

*[NIH grants dataset](/datasets/nih-grants) · CC0 1.0*
