# implementation

> **NIH NIH U54** · STANFORD UNIVERSITY · 2020 · $178,201

## Abstract

Abundant evidence documents persistent and pervasive health and health care disparities across the 
lifecourse in the United States, especially according to race/ethnicity and socioeconomic status. The primary 
objective of the SPHERE (Stanford Precision Health Equity in Race and Ethnicity) Implementation Core is to 
promote effective dissemination and adoption of precision health approaches to decrease health disparities at 
the local, regional, state, and national levels. Precision health includes disease prevention and treatment for 
maintenance of health and wellness across the lifecourse that is proactive, predictive, effective, efficient, and 
equitable. Precision health holds great potential for revolutionizing health disparities research and interventions 
through a better understanding of the complex interplay between biological, behavioral, environmental, and 
social factors that contribute to health inequalities and influence population health. Taking into consideration 
root causes, the implementation Core will use a socio-ecological framework that conceptualizes health and 
wellness as a product of biological, behavioral, environmental, and social factors. Additionally, the 
Implementation Core will engage patients, community organizations, and key stakeholders from health 
disparities community in all phases of the Implementation Core activities in accordance with principles of 
community-based participatory research and patient engagement. 
 In close collaboration with consortium partners, the strategies that are developed, implemented, and 
evaluated as part of this core will build upon findings from the individual research projects to promote 
dissemination and implementation at the local, regional, and national levels to directly reduce health 
disparities. In support of the proposed projects, the Implementation Core's objectives are to: 1) Develop and 
evaluate the SPHERE ethical guidelines for participation in precision health research and delivery of precision 
health approaches among American Indians, Latinos, and Asians; 2) Establish a “Precision Health Innovation 
Lab” in Stanford Primary Care where precision health implementation strategies can be rapidly tested and 
refined among racial/ethnic minority and low-income patients. 3) Systematically assess the potential for 
dissemination and implementation of precision health interventions with mixed methods using the RE-AIM 
(Reach, Effectiveness, Adoption, Implementation, and Maintenance) model among American Indians, Latinos, 
and Asians; and 4) Develop, implement, and evaluate a precision health-training curriculum for providers that 
serve racial/ethnic minority and low-income patients in community settings. Through the development of ethical 
principles, evidence to support implementation and dissemination, and capacity building resources and 
activities, the Implementation Core will effectively translate findings from the SPHERE studies into community- 
based strategi...

## Key facts

- **NIH application ID:** 9896675
- **Project number:** 5U54MD010724-05
- **Recipient organization:** STANFORD UNIVERSITY
- **Principal Investigator:** Lisa Goldman Rosas
- **Activity code:** U54 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $178,201
- **Award type:** 5
- **Project period:** — → 2024-08-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/9896675

## Citation

> US National Institutes of Health, RePORTER application 9896675, implementation (5U54MD010724-05). Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/grant/nih/9896675. Licensed CC0.

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