# Patient Outcomes Following Total Joint Replacement Surgery: A Comparison of Hospitals and Ambulatory Surgery Centers

> **NIH NIH R03** · BOSTON UNIVERSITY MEDICAL CAMPUS · 2020 · $82,500

## Abstract

Project Summary/Abstract
CMS recently began paying for total knee replacement surgery (arthroplasty; TKA) performed in
hospital outpatient departments (HOPDs) and is considering reimbursing for HOPD total hip
arthroplasty (THA). Many observers expect Medicare payment for TKA and THA in ambulatory
surgery centers (ASCs) to follow. Currently, total joint replacements are being performed on
commercially insured patients in HOPDs and in a growing number of ASCs. However, despite
claims by physician-owners of ASCs that outpatient total joint replacement is appropriate and
safe for a large portion of candidates, evidence to date is based on a limited set of studies using
very small samples of patients treated in HOPDs. As ASCs have steadily expanded their
business and taken on increasingly complex surgeries, some experts fear they overlook high-risk
health problems. Yet it is possible that comparable outcomes can be achieved with less reliance
on traditional health system resources. The majority of joint replacement recipients in the U.S.
are Medicare beneficiaries, and outcomes data on outpatient TKA in this population will not be
available for some time. In the interim, we propose to compare TKA and THA outcomes and
payments across inpatient, HOPD, and ASC settings using a large sample of commercially-
insured patients. We will identify near elderly patients who underwent TKA or THA in an
inpatient or outpatient ASC setting during 2014-2019 and who were continuously enrolled for
90 days following surgery. We will select matched samples of patients across inpatient, HOPD
and ASC settings using propensity score techniques, matching with risk scores generated from
the HHS Hierarchical Condition Categories risk adjustment model which was designed under
the ACA for application to the commercially-insured population. We will identify cases of
related 30-day and 90-day readmission, and cases within 90-days of revision surgery, surgical
site infection, deep-vein thrombosis, pulmonary embolism, and dislocation/loosening/breakage
of prosthesis. We will test differences across sites using statistical techniques. Finally, we will
measure the relative cost of episodes of care including related expenditures incurred during the
90-day post-inpatient stay or ASC encounter. This project will enlighten CMS on potential
health consequences of further transitions to outpatient surgery. For providers, it will identify
areas of potential patient safety lapses, and targets for interventions. Finally, it will facilitate
patient engagement in their care by informing “gray area” candidates for outpatient joint
replacement in making wiser decisions about where to undergo surgery.

## Key facts

- **NIH application ID:** 9896744
- **Project number:** 5R03AG062926-02
- **Recipient organization:** BOSTON UNIVERSITY MEDICAL CAMPUS
- **Principal Investigator:** Kathleen Carey
- **Activity code:** R03 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $82,500
- **Award type:** 5
- **Project period:** 2019-04-01 → 2020-12-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/9896744

## Citation

> US National Institutes of Health, RePORTER application 9896744, Patient Outcomes Following Total Joint Replacement Surgery: A Comparison of Hospitals and Ambulatory Surgery Centers (5R03AG062926-02). Retrieved via AI Analytics 2026-05-21 from https://api.ai-analytics.org/grant/nih/9896744. Licensed CC0.

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