# Core B: Clinical Core

> **NIH NIH U19** · MASSACHUSETTS GENERAL HOSPITAL · 2020 · $373,297

## Abstract

Project Summary
This U19 aims to determine how PD-1 blockade affects human immune responses induced by chronic viruses
and vaccines. The Clinical Core of the proposed MGH-UPenn PRIG will be central to the scientific efforts of this
consortium. A unique and expansive sample repository has been created over the last 18 years and well-
characterized for clinical, immune, and genetic data. This repository will be maintained and crucially expanded
to include longitudinal samples from individuals undergoing immunotherapies via clinical infrastructures at both
MGH and UPenn. This concerted effort will maintain a high throughput of sample availability to catalyze scientific
efforts across the consortium, including tracking samples to investigators in Projects 1 and 2 and Cores C and
D.

## Key facts

- **NIH application ID:** 9897489
- **Project number:** 5U19AI082630-12
- **Recipient organization:** MASSACHUSETTS GENERAL HOSPITAL
- **Principal Investigator:** ARTHUR Y KIM
- **Activity code:** U19 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $373,297
- **Award type:** 5
- **Project period:** — → —

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/9897489

## Citation

> US National Institutes of Health, RePORTER application 9897489, Core B: Clinical Core (5U19AI082630-12). Retrieved via AI Analytics 2026-05-21 from https://api.ai-analytics.org/grant/nih/9897489. Licensed CC0.

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