# Administrative Core (Cornelissen)

> **NIH NIH U19** · GEORGIA STATE UNIVERSITY · 2020 · $666,887

## Abstract

The overall goal of the International Center for Gonococcal Vaccine Discovery, Formulation and
Implementation (ICGV) is to employ our established pipeline for vaccine antigen discovery to optimize the
antigenic properties of our selected outer membrane protein antigens as possible vaccine components.
Furthermore, our Center will utilize antigen diversity, global strain heterogeneity, and public acceptance
information to generate improved computer models that allow us to predict the success of any Ngo vaccine
deployed. The infrastructure and collaborations to enable success for projects and cores described in this
Center are already in place. The goal of the Administrative Core is to ensure that the ICGV is productive in its
goals towards rational engineering of our selected Ngo outer membrane protein antigens and deploying
predictive modeling approaches to integrate sequence and strain diversity with public opinion on STI vaccines.
The Administrative Core consists of the project and core leadership and a Core Administrator, and this group
will be supplemented by a panel of renowned vaccine experts as an external Scientific Advisory Board. The
specific aims of the Administrative Core are as follows: Aim 1. Provide coordination, supervision and
management that streamlines oversight of Center activities, while incentivizing synergistic and creative
approaches to achieving project milestones and objectives. Aim 2. Coordinate regulatory responsibilities of the
Center, including human subjects, animal subjects, training, compliance and NIH-related activities including
production of progress reports. Aim 3. Foster collaboration with other cores, including planning and supporting
multi-Center meetings. Aim 4. Function as an interface between projects, cores, the Scientific Advisory Board,
CRC executive committee and NIH/NIAID staff. Aim 5. Establish realistic timelines and monitor progress
towards these goals. When necessary, alternative strategies will be implemented to reach the project
milestones. Aim 6. Provide financial oversight of all projects and cores. Aim 7. Provide an environment
conducive to collaboration among the Core and Project investigators, ensuring investigators receive
appropriate recognition for their contributions to this complex team-based project. Aim 8. Implement the
Development and Research Program (DRP) to permit a competitive application process that will identify
promising young investigators and fund their Ngo-based vaccine development projects that will ultimately feed
into our pipeline and modeling. Innovative aspects of the Administrative Core include: the highly experienced
PI and the well-established collaborations of PI with the project/core leads; the established pipeline for vaccine
antigen discovery; the integration and deployment of an external Scientific Advisory Board; and the
supplemental funding for the Development and Research Program committed by the Office of Research and
Innovation at Virginia Commonwealth ...

## Key facts

- **NIH application ID:** 9899919
- **Project number:** 5U19AI144182-02
- **Recipient organization:** GEORGIA STATE UNIVERSITY
- **Principal Investigator:** CYNTHIA N CORNELISSEN
- **Activity code:** U19 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $666,887
- **Award type:** 5
- **Project period:** — → —

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/9899919

## Citation

> US National Institutes of Health, RePORTER application 9899919, Administrative Core (Cornelissen) (5U19AI144182-02). Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/grant/nih/9899919. Licensed CC0.

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