BIOINFORMATICS CORE SUMMARY/ABSTRACT In the previous phase of SD BRIN, the Bioinformatics Core team proposed the following primary goals: 1) provide online library resources; 2) provide comprehensive bioinformatics educational resources and opportunities; 3) support individual research projects; 4) support collaborative, multidisciplinary research, 5) facilitate data management, and 6) maintain and enhance the University of South Dakota’s research cyber-infrastructure. Note: Our original BRIN proposal described a Bioinformatics Core collaboration with University of Nebraska Omaha. Due to administrative changes in the UNO BRIN program, the Bioinformatics Core instead, developed a strong collaboration with the South Dakota NSF EPSCOR project.