# Scientific Core

> **NIH NIH U19** · JOHNS HOPKINS UNIVERSITY · 2020 · $279,095

## Abstract

Scientific Core Summary 
The Scientific Core is designed to successfully recruit and monitor HCV-antibody-negative 
young injection drug users for HCV infection and to clinically characterize acute infection and 
identified by testing sera for HCV RNA and seroconversion, and persons with acute infection will 
be clinically characterized by serial ALT and HCV RNA testing. The infrastructure of the Core is 
necessary for completion of the first trial of an HCV vaccine in people at risk of HCV infection 
and will be useful in potential future trials of HCV vaccines. Plasma, serum, and PBMC will be 
collected and stored in the repository for use in Projects 1-3, as well as for other proposed 
projects in the Cooperative Research Centers (CRC), including those of Dr.'s Walker, Gale, and 
Lauer (see LOS provided for their applications). It is also anticipated that these specimens will 
be shared with NIH- funded investigators outside the CRC. Based on almost 15 years of 
experience, this Core will be a highly successful component of this CRC.

## Key facts

- **NIH application ID:** 9900736
- **Project number:** 5U19AI088791-10
- **Recipient organization:** JOHNS HOPKINS UNIVERSITY
- **Principal Investigator:** ANDREA L COX
- **Activity code:** U19 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $279,095
- **Award type:** 5
- **Project period:** — → —

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/9900736

## Citation

> US National Institutes of Health, RePORTER application 9900736, Scientific Core (5U19AI088791-10). Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/grant/nih/9900736. Licensed CC0.

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