# Core C - Stem Cell Core

> **NIH NIH P01** · AUGUSTA UNIVERSITY · 2020 · $283,576

## Abstract

The main function of the Bone Stem Cell Core (Core C) is to isolate and distribute bone marrow-
derived mesenchymal stem/progenitor cells (BMSCs) to the investigators of the individual
projects, and to provide technical support for use of the cells. A key component essential to the
success of the proposed Program Project is the availability of BMSCs because all projects
require these cells. Thus, a centralized Core facility for the production of quality cells is crucial
to the success of this dynamically coordinated Program Project. This Core will benefit the
research efforts of individual investigator by reducing costs, providing quality control for study
procedures, and enhancing collaborations among multiple disciplines to achieve greater
scientific gain through an integrated approach. In addition, production and distribution of cells
from a centralized facility will ensure that all studies start with cells of the same lineages and
background. The Specific Aims are: 1. Isolate, characterize and distribute mouse BMSCs,
human bone marrow MSCs (hMSCs), and 2. Provide ongoing technical support for hypoxic and
conventional MSC culture and differentiation (osteogenic, adipogenic, and chondrogenic)
assays. By achieving these objectives, this Core will function as a unique resource to provide
mouse and human BMSCs and technical assistance to the individual projects, as well as to
other Georgia Regents University investigators who are interested in studies related to aging,
metabolic bone diseases, or stem cell research.

## Key facts

- **NIH application ID:** 9902284
- **Project number:** 5P01AG036675-09
- **Recipient organization:** AUGUSTA UNIVERSITY
- **Principal Investigator:** XINGMING SHI
- **Activity code:** P01 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $283,576
- **Award type:** 5
- **Project period:** — → —

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/9902284

## Citation

> US National Institutes of Health, RePORTER application 9902284, Core C - Stem Cell Core (5P01AG036675-09). Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/grant/nih/9902284. Licensed CC0.

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