# Core-005

> **NIH NIH P42** · UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR · 2020 · $44,807

## Abstract

The UNM Metal Exposure and Toxicity Assessment on Tribal Lands in the Southwest (METALS) Superfund 
Research Program (SRP) and Training Center will focus on risk reduction for Native Americans exposed to 
hazardous metals mixtures from abandoned uranium mine waste. This will be the ONLY SRP Center focused 
on risks to Native American communities. Specifically, UNM METALS will focus on site-specific 
physical/mineralogic/biogeochemical properties of the waste that alter immune function and DNA repair in tribal 
populations. The biomedical research proposed in UNM METALS focuses on major uncertainties in these 
exposure:outcome relationships, while environmental projects complement this research by exploiting 
characteristics that impact mobility and toxicity to develop and test novel cost-effective metals immobilization 
and removal strategies to reduce risks in ways compatible with tribal culture, and design risk 
avoidance/warning systems. Recognizing that complete remediation of these sites under CERCLA remains 
decades away, METALS will use multi-directional community engagement and research translation cores to 
develop and implement trans-generational approaches to risk communication and risk avoidance that integrate 
indigenous learning models (e.g. tribal ecological knowledge) and Western science. The METALS Center will 
integrate training of junior faculty and graduate students with multi-directional training of community members 
and research staff so that local knowledge of mining impacts and health problems inform air and water 
monitoring needs to support the environmental and biomedical research projects and build a foundation of 
transdisciplinary, partnered research for the next generation. METALS will utilize committed pilot funding from 
the UNM Cancer Center, the HSC Research Office, and our Environmental Health Signature Program to build 
transdisicplinary partnerships that expand our team to respond to additional health outcomes of community 
concern. The Center will expand ongoing, developed partnerships with three Native American communities 
living in close proximity to unique waste sites. The first is Laguna Pueblo living with the abandoned > 8000 
acre openpit Jackpile Mine listed on the Superfund National Priorities List, and two Navajo communities living 
in proximity to two separate sites being addressed through CERCLA assessment as part of the USEPA 
Congressionally mandated Five-Year Plan to Address Uranium Contamination on the Navajo Nation: Red 
Water Pond Road adjacent to the North East Church Rock Mine; and Tachee-Blue Gap community living next 
to the Claim 28 waste site. In summary, we will work closely with communities, tribal and federal agencies to 
develop informed Superfund prioritization based on site-specific factors identified through our research, and 
develop solutions that build on site properties to immobilize and remove metals, reduce risk in ways that are 
holistic, predictable and sustainable, an...

## Key facts

- **NIH application ID:** 9903358
- **Project number:** 5P42ES025589-04
- **Recipient organization:** UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR
- **Principal Investigator:** Johnnye L Lewis
- **Activity code:** P42 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $44,807
- **Award type:** 5
- **Project period:** — → —

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/9903358

## Citation

> US National Institutes of Health, RePORTER application 9903358, Core-005 (5P42ES025589-04). Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/grant/nih/9903358. Licensed CC0.

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