# Sample and Data Management Core

> **NIH NIH P42** · UNIVERSITY OF LOUISVILLE · 2020 · $83,578

## Abstract

ABSTRACT
The primary objective of the Sample and Data Management Core (SDMC) is to provide support to each of the
four projects of the Louisville Superfund Center. The functions of the Core are matched to the needs of each
project and cover a full range of services from collaboration and routine service to protocol preparation to
procedural review and oversight. The Core will provide two main services: it will establish a repository for the
long-term storage and archiving of samples and data; and it will assist Center investigators in the statistical
analysis of their results. The core will assure the authenticity and quality of these specimens and it will prepare
these samples for long-term storage, or dispense samples as needed. The Core will also provide scientifically
valid and rigorous statistical analysis of data and support the development of innovative methods to enhance the
basic and translational research efforts of Center investigators. The Core will provide state-of-the-art biostatistics
and bioinformatics expertise and analytical support. Core biostatisticians will also develop new statistical
methods, such as quantitative risk assessment models, for estimating cardiometabolic disease risk in exposed
populations and for the analysis and evaluation of exposures and health consequences. In addition, the core
will develop novel methods for the analysis of multi-pollutant exposures as they relate to health outcomes. The
core will serve as a unique educational resource for training graduate students, post-doctoral fellows, residents
and junior faculty and in collaboration with the Training and Administration Cores. This Core will allow Center
investigators easy access to high quality, centralized data management and statistical services, and thereby will
strengthen the organizational cohesion of the Center. This comprehensive and integrated service permits one
or more biostatisticians to be involved from the initial planning stage of a project (when statistical consultation is
most beneficial) throughout its implementation, analysis and completion. The Core will provide a stable and
collegial environment that fosters long-term working relationships between biostatisticians and investigators, and
continues to promote sophisticated approaches to experimental design and analysis. The biostatisticians of this
Core are knowledgeable about clinical research and have broad expertise in statistical applications for
epidemiological investigations, clinical trials, pre-clinical studies, and prevention and control research. Their
interdisciplinary interactions with basic scientists and clinical investigators will add a new dimension to the
interpretation of experimental results, one that is only possible when collaborators share a mutual appreciation
of problems and issues.

## Key facts

- **NIH application ID:** 9904684
- **Project number:** 5P42ES023716-04
- **Recipient organization:** UNIVERSITY OF LOUISVILLE
- **Principal Investigator:** Shesh N. Rai
- **Activity code:** P42 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $83,578
- **Award type:** 5
- **Project period:** — → —

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/9904684

## Citation

> US National Institutes of Health, RePORTER application 9904684, Sample and Data Management Core (5P42ES023716-04). Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/grant/nih/9904684. Licensed CC0.

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