# UW Center for Translational Muscle Research (Overall Application)

> **NIH NIH P30** · UNIVERSITY OF WASHINGTON · 2020 · $860,340

## Abstract

ABSTRACT - Overall
The University of Washington (UW) is internationally known for its excellence in all aspects of skeletal muscle
biology, especially in mechanistic and translational research of diseases. However, there is currently no
centralizing resource that brings together all the muscle investigators from multiple departments for the benefit
of facilitating and accelerating their efforts. Therefore we propose the UW Resource Center for Translational
Muscle Research (CTMR) to provide a unifying resource and state of the art approaches to enhance skeletal
muscle research at the UW. The proposed Center will offer tools, facilities and expertise in a combination
available only at the UW to facilitate novel insights to muscle pathologies and move new therapeutics towards
the clinic and the marketplace. This new Center will offer 4 cores (one administrative and three research
resource) to provide tools and expertise in several areas of interest to current principal investigators. The
Administrative Core (A) will provide program management and enrichment by providing a pilot project program,
workshops, a seminar series, training and educational opportunities for new investigators and more experienced
investigators moving into muscle research. The Mechanics and Devices Core (B) will provide state of the art
measurements of muscle biomechanics at multiple levels of integration, and develop new assays for maturation
and assessment of early stage muscle. The Metabolism and Energetics Core (C) will provide tools for in depth
measures and analysis of metabolomics, energetics, cell respiration and mitochondrial function. The
Computational and Quantitative Analysis Core (D) will provide computational and statistical tools for
understanding disease, suggesting new therapeutic targets and understanding mechanisms. The CTMR will
offer an environment to facilitate using integrative analysis, from single molecule dynamics through muscle
structure-function relationships, with interdisciplinary approaches to advance skeletal muscle disease research
and therapeutics development.

## Key facts

- **NIH application ID:** 9908045
- **Project number:** 5P30AR074990-02
- **Recipient organization:** UNIVERSITY OF WASHINGTON
- **Principal Investigator:** THOMAS L. DANIEL
- **Activity code:** P30 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $860,340
- **Award type:** 5
- **Project period:** 2019-04-05 → 2024-02-29

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/9908045

## Citation

> US National Institutes of Health, RePORTER application 9908045, UW Center for Translational Muscle Research (Overall Application) (5P30AR074990-02). Retrieved via AI Analytics 2026-05-22 from https://api.ai-analytics.org/grant/nih/9908045. Licensed CC0.

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