# Diabetes Prevention Culturally Tailored for Mexican Americans

> **NIH NIH R01** · UNIVERSITY OF TEXAS AT AUSTIN · 2020 · $591,337

## Abstract

ABSTRACT
Starr County is a poor Texas-Mexico border community that is 98% Mexican American and has the highest
diabetes-related death rate in Texas. In previous Starr County studies, we tested interventions culturally
tailored for Spanish-speaking Mexican Americans diagnosed with type 2 diabetes (T2DM). Each study
participant was supported by a family member who also received program benefits; 70% of these supporters
did not have diabetes. Compared to the control group, fewer non-diabetic supporters in the experimental
group converted to diabetes by 12 months post study entry. The primary purpose of the proposed study is to
test the effectiveness of our culturally tailored DSME intervention that will be adapted for preventing, or at
least delaying, diabetes onset in Mexican Americans with prediabetes. The intervention will involve: 1) 12 2-
hour weekly group educational sessions that emphasize eating and preparing healthy Mexican-American
foods and increasing physical activity; 2) 15 2-hour bi-weekly/monthly support group sessions on problem
solving the barriers to adopting healthier lifestyles; and 3) 3 booster sessions held at 6-month intervals. We
will integrate aspects of the Diabetes Prevention Program, as well as motivational interviewing, and prior to
intervention testing, we will conduct focus groups with key individuals in Starr County to confirm the strategy
and obtain community support. Intervention effectiveness will be examined using a randomized, repeated
measures, pretest/posttest control group design, with an “enhanced” usual care control group. We will enroll
300 Mexican Americans with verified prediabetes from rosters of ongoing Starr County genetic studies.
Groups of 10 will be constituted according to the area of the county in which people live; each group will be
randomly assigned to experimental or control conditions. Growth curve analysis, using multilevel models, will
be used to compare intervention effects on health outcomes over time. We hypothesize that participants in
the experimental group, compared to the control group, will have better health outcomes (A1C, FBG, lipids,
BP, physical activity, dietary intake, and anthropometric variables [BMI, waist circumference]) at 3, 6, 12, 24,
and 36 months post baseline, as well as lower rates of converting to T2DM (OGTT) by 36 months. This study
is a significant step in our plan to develop effective culturally tailored health programs for populations at high
risk for T2DM.

## Key facts

- **NIH application ID:** 9908068
- **Project number:** 5R01DK109920-04
- **Recipient organization:** UNIVERSITY OF TEXAS AT AUSTIN
- **Principal Investigator:** SHARON A BROWN
- **Activity code:** R01 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $591,337
- **Award type:** 5
- **Project period:** 2017-04-15 → 2022-03-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/9908068

## Citation

> US National Institutes of Health, RePORTER application 9908068, Diabetes Prevention Culturally Tailored for Mexican Americans (5R01DK109920-04). Retrieved via AI Analytics 2026-05-21 from https://api.ai-analytics.org/grant/nih/9908068. Licensed CC0.

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