# Rheumatology Informatics System for Effectiveness Patient-Reported Outcome (RISE-PRO) Dissemination Project

> **NIH AHRQ R18** · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · 2020 · $493,891

## Abstract

PROJECT SUMMARY
Patient-reported outcomes (PROs) are important in rheumatoid arthritis (RA), a condition that affects 1.3
million Americans and is a leading cause of disability. Among chronic conditions, RA has many decades of
robust scientific evidence around the validity of PROs. PROs are key outcome measures in RA clinical trials
and studies, are responsive to therapy changes, are strong predictors of future disability and mortality, and
play a central role in facilitating shared decision-making and treatment. Advances in health information
technology (IT), like electronic health record-enabled Qualified Clinical Data Registries (QCDRs), provide an
opportunity to scale and spread of use of PRO measures nationally. The Rheumatology Informatics System for
Effectiveness (RISE) registry is a QCDR that was established in 2014 to improve the quality of care for patients
seen in rheumatology practices. The RISE informatics platform aggregates electronic health record data from
participating practices, analyzes these data centrally and feeds performance on quality measures back to
clinicians using a web-based dashboard. RISE currently includes one the largest PRO measurement efforts for
ambulatory patients with a chronic disease in the United States. However, as the registry matures, several
critical gaps remain in our national PRO measurement efforts, including the lack of representation of public
hospital systems and at-risk populations, the challenges faced by some practices in creating structured data
fields in electronic health records to capture PRO measure scores, and the need to evaluate the impact of the
PRO collection efforts through RISE. The overarching goal of this proposal is to systematically address each of
these issues by 1) creating an evidence-based clinical learning network to support the participation of public
hospital systems in PRO measurement and improvement efforts through RISE, 2) developing and scaling a
natural language processing system to extract PRO measures from unstructured data in clinical notes, and 3)
analyzing the impact of PRO measurement through RISE on quality of care and health outcomes in RA. This
proposal builds on the novel informatics platform of the RISE registry to scale, spread and evaluate PRO
implementation across a nationwide network of rheumatology practices, with the ultimate goal of improving
functional status outcomes for those with RA.

## Key facts

- **NIH application ID:** 9912121
- **Project number:** 5R18HS025638-03
- **Recipient organization:** UNIVERSITY OF CALIFORNIA, SAN FRANCISCO
- **Principal Investigator:** Jinoos Yazdany
- **Activity code:** R18 (R01, R21, SBIR, etc.)
- **Funding institute:** AHRQ
- **Fiscal year:** 2020
- **Award amount:** $493,891
- **Award type:** 5
- **Project period:** 2018-07-01 → 2022-04-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/9912121

## Citation

> US National Institutes of Health, RePORTER application 9912121, Rheumatology Informatics System for Effectiveness Patient-Reported Outcome (RISE-PRO) Dissemination Project (5R18HS025638-03). Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/grant/nih/9912121. Licensed CC0.

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