# Cluster C: 8 Tissue Procurement

> **NIH NIH P30** · UNIVERSITY OF IOWA · 2020 · $72,162

## Abstract

The Tissue Procurement Core (TPC) assists HCCC members in the collection, storage, and distribution of 
malignant and non-malignant human biomaterials. The overarching goal of the TPC is to provide HCCC 
members with IRB-compliant, clinically annotated, quality-ensured biomaterials to facilitate their research 
objectives and to maintain a cutting-edge perspective on biobanking best practices for the HCCC. It provides 
quality-controlled, IRB-approved 1) fresh and frozen tumor tissue, 2) blood and DNA samples from cancer 
patients, and 3) formalin-fixed paraffin-embedded cancer tissue from the Department of Pathology and the 
Iowa Residual Tissue Repository and Virtual Tissue Repository. The TPC works with other HCCC units to 
annotate samples with relevant clinical information including the Molecular Epidemiology Resource, the 
Population Research Core and the Clinical Trials Support Office to meet the needs of individual HCCC 
members and groups conducting basic, translational and population-based cancer research studies. In 
addition, the TPC has supplied quality-ensured tissue resources to national efforts such as The Cancer 
Genome Atlas (TCGA) project and the NCI patient-derived xenograft (PDX) program. The TPC is integrally 
connected to broader Carver College of Medicine biobanking efforts through UI Bioshare, a major institutional 
initiative in which significant investment has been made to provide an institution-wide biomaterial database 
management tool and to enable the efficient connection of biomaterials to clinical data from the electronic 
medical record held in the UIHC EPIC information system. In 2014 the TPC collected biomaterials from 
552 cases for the HCCC, and distributed 865 biomaterials to HCCC members from all 4 programs.

## Key facts

- **NIH application ID:** 9914249
- **Project number:** 5P30CA086862-20
- **Recipient organization:** UNIVERSITY OF IOWA
- **Principal Investigator:** Charles Michael Knudson
- **Activity code:** P30 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $72,162
- **Award type:** 5
- **Project period:** — → —

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/9914249

## Citation

> US National Institutes of Health, RePORTER application 9914249, Cluster C: 8 Tissue Procurement (5P30CA086862-20). Retrieved via AI Analytics 2026-06-11 from https://api.ai-analytics.org/grant/nih/9914249. Licensed CC0.

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