# Cluster C: 10 Population Research

> **NIH NIH P30** · UNIVERSITY OF IOWA · 2020 · $72,639

## Abstract

The Population Research Core (PopRC) is a centralized resource dedicated to the needs of the Holden 
Comprehensive Cancer Center (HCCC) in the domain of population science. Quality epidemiology support 
promotes strong observational study designs and data collection and data curation methods. The PopRC 
provides this support in close collaboration with HCCC members and the Tissue Procurement Core, Molecular 
Epidemiology Resource, and Biostatistics Core. The primary resources of the PopRC are its scientific 
personnel and its curated and annotated population-based data. The PopRC provides HCCC members with 
guidance and assistance in accessing and using large databases of cancer patient data that include SEER- 
Medicare, SEER-Medicare Health Outcomes Study (MHOS), enhanced unlinked SEER research dataset, Iowa 
driver's license database, the Iowa Mortality database, the Greater Plains Collaborative, and others. A number 
of these resources are unique to the HCCC catchment area (the state of Iowa). In addition to database 
research activities, the PopRC supports personnel with a wide range of expertise including population study 
designs, field research methods and tools, and biospecimens linked to clinical registries. PopRC personnel 
collaborate closely with the Biostatistics Core on analytic plans and data analysis of population studies, and 
with the Tissue Procurement Core and Molecular Epidemiology Resource to ensure efficient and effective 
coordinated access for investigators to biospecimens. The PopRC collaborates with the Tissue Procurement 
Core by providing samples from the Iowa Residual Tissue Repository and Virtual Tissue Repository that are 
linked to SEER data. The PopRC supports HCCC members from all four research programs, with 62 percent 
of the users of the facility being HCCC members. Projects commonly involve collaborations of HCCC 
epidemiologists with clinician and basic scientists across the HCCC and from other academic institutions. 
Plans in the upcoming funding period include enhancing access by HCCC members to robust clinical data 
linked to unique tissue resources. In summary, the PopRC is a comprehensive, collaborative and integrated 
resource that is vital to the HCCC.

## Key facts

- **NIH application ID:** 9914251
- **Project number:** 5P30CA086862-20
- **Recipient organization:** UNIVERSITY OF IOWA
- **Principal Investigator:** BRADLEY D MCDOWELL
- **Activity code:** P30 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $72,639
- **Award type:** 5
- **Project period:** — → —

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/9914251

## Citation

> US National Institutes of Health, RePORTER application 9914251, Cluster C: 10 Population Research (5P30CA086862-20). Retrieved via AI Analytics 2026-06-11 from https://api.ai-analytics.org/grant/nih/9914251. Licensed CC0.

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