# Postdoctoral Training in the Biology of Drug Abuse

> **NIH NIH T32** · UNIVERSITY OF MICHIGAN AT ANN ARBOR · 2020 · $433,473

## Abstract

Abstract
The overall purpose of this training grant is to provide postdoctoral training to young basic
scientists and physicians in the area of neurobiology of substance abuse, with a focus on the
mode of action of psychostimulant and opiate drugs at the genetic, molecular, circuit and
behavioral levels. Our objective is to provide an exciting and innovative environment with world
class facilities and faculty to develop the next generation of scientists working in drug abuse.
Training will take place in the multidisciplinary setting at the University of Michigan. The faculty
members are all NIDA grantees (or co-Investigators) and have expertise in the neurobiology of
substance abuse, with particular emphasis on the area of opioid and psychostimulant drugs.
The focus of the proposal is the training of postdoctoral fellows in state-of-the-art approaches for
studying mechanisms underlying abuse of psychoactive drugs. This includes studying the
genetic, developmental and environmental factors that lead to vulnerability to substance abuse;
the mode of action of drugs of abuse at the molecular, cellular, anatomical and behavioral
levels; and the long-term consequences of psychoactive drugs on the brain, as mediated
through mechanisms of neural plasticity; and the development of medications, and prevention
strategies. The working assumption is that the functional and structural brain remodeling
associated with chronic drug use lies at the basis of tolerance, sensitization, physical
dependence, and psychological addiction to these drugs. The drug abuse research community
at the University of Michigan is of high quality and has a long history in the field. Beyond their
individual strengths, the training faculty members have long-standing collaborative scientific and
training relationships with each other. These historical strengths have recently been further
enhanced with a number of initiatives at the University of Michigan, designed to facilitate life
science research in general, and neuroscience research in particular. They include state-of-the-
art tools for mouse and rat genetics, genomics, proteomics, and informatics. Thus, our
postdoctoral fellows will profit from a highly sophisticated, yet supportive, research and training
environment.

## Key facts

- **NIH application ID:** 9916730
- **Project number:** 5T32DA007268-29
- **Recipient organization:** UNIVERSITY OF MICHIGAN AT ANN ARBOR
- **Principal Investigator:** John R. Traynor
- **Activity code:** T32 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $433,473
- **Award type:** 5
- **Project period:** 1991-09-30 → 2022-06-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/9916730

## Citation

> US National Institutes of Health, RePORTER application 9916730, Postdoctoral Training in the Biology of Drug Abuse (5T32DA007268-29). Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/grant/nih/9916730. Licensed CC0.

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