# Environmental influences on pregnancy outcomes after Hurricane Michael

> **NIH NIH R21** · TULANE UNIVERSITY OF LOUISIANA · 2020 · $229,283

## Abstract

The natural world and human influences work together to create the devastation that follows a major 
disaster such as a hurricane.  Although many studies have examined broad patterns of effects on 
pregnancy outcomes after disasters, the causes of adverse outcomes are not always clear, as there 
are interrelated environmental pollutant exposures, psychological stressors, and lack of health 
care. Without understanding which aspects of disaster exposure are the strongest contributors to 
adverse outcomes, it will not be possible to establish disaster responses that efficiently target 
the most important factors. The objective of this application is to examine effects of 
environmental (harmful algal bloom, carbon monoxide) exposures and generally encountered disaster 
exposures (power outages, storm damage) on pregnancy-related outcomes.  Our central hypothesis is 
that severe exposure (defined by both magnitude and duration) to any of these stressors will be 
associated with worse outcomes.  Our specific aims are to 1) Examine the relationship between 
environmental exposures (HAB and CO) and birth outcomes; 2) Assess the relationship between general 
disaster-related exposures (extent of damage, health care closings) and birth outcomes; 3) 
Determine which disaster- related exposures most strongly predict birth outcomes, and the combined 
effect of environmental and general disaster exposure; 4) Engage primary care practitioners to 
build EOH knowledge and skills by developing CME content on HAB and CO. We will accomplish these 
specific aims by comparing birth outcomes in areas exposed to these environmental predictors to 
areas and times that are unexposed. We will map exposure patterns based on ecological sampling and 
satellite-based estimates (HAB), CO surveillance data and poison control centers data, and 
hurricane damage reports (state of the art satellite measurements, disaster declarations, power 
outage data, health facility closing) and physical impacts measurements (storm surge inundation, 
wind speed, land cover change).  Comparisons will be made across and within areas exposed to 
different levels of environmental contaminants, as well as pre-post hurricane.  To promote 
translation and dissemination, we will develop CME content targeting the potential risks adverse 
pregnancy and birth outcomes associated with exposures to HAB and CO. At the end of the project, 
our expected outcome is to have identified the aspects of Hurricane Michael most associated with 
adverse birth outcomes.  The proposed research represents a three-pronged innovative design- 
conceptually, by determining the potential cumulative risk of two integrated exposure domains - 
environmental contaminants and traditional disaster; methodologically, by using Synthetic Aperture 
Radar data to examine exposures to HAB during pregnancy in humans; and 3) translational, by 
utilizing time sensitive disaster-related environmental health findings for frontline CME.

## Key facts

- **NIH application ID:** 9918368
- **Project number:** 5R21ES031020-02
- **Recipient organization:** TULANE UNIVERSITY OF LOUISIANA
- **Principal Investigator:** Emily Wheeler Harville
- **Activity code:** R21 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $229,283
- **Award type:** 5
- **Project period:** 2019-04-18 → 2022-03-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/9918368

## Citation

> US National Institutes of Health, RePORTER application 9918368, Environmental influences on pregnancy outcomes after Hurricane Michael (5R21ES031020-02). Retrieved via AI Analytics 2026-05-25 from https://api.ai-analytics.org/grant/nih/9918368. Licensed CC0.

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