# Training in HIV Replication and Pathogenesis

> **NIH NIH T32** · UNIVERSITY OF ROCHESTER · 2020 · $193,559

## Abstract

While the HIV/AIDS pandemic continues, the incidence of HIV infections has fallen because of the
deployment of antiviral drugs and multiple prevention modalities. Recent research successes in targeting
complete elimination of HIV, development of novel vaccines and therapeutics, and progress in treating and
preventing HIV-associated comorbidities, makes this an exciting time in HIV/AIDS research – but continued
progress will require interdisciplinary, collaborative efforts by highly trained, expert scientists. The goal of this
proposal is to prepare young scientists for that role. Particularly, we will prepare predoctoral students for
leadership roles in HIV/AIDS research, through an innovative training program that will provide comprehensive,
professional and technical skills and knowledge, in an autonomy-supportive environment that encourages self-
directed exploration of learning paths relevant to the full range of research careers. Hands-on research
training will be conducted in an outstanding scientific milieu that focuses on key strengths of the University of
Rochester (UR)'s Center for AIDS Research (CFAR) and high priority areas (as defined by NIH): (1) cure
research, including HIV RNA Biology and the central nervous system (CNS) reservoir of infection; (2) end
organ disease and aging, including cardiovascular and CNS disease; (3) prevention research, including
vaccines and novel therapeutics. This T32 program will incorporate instruction in professional skills, structured
research career development paths, experiential learning opportunities, and a mentor training program
intended to ensure an autonomy-supportive learning environment that encourages self-directed learning and
exploration of diverse career options. Finally, new program-specific courses have been added, while the
overall graduate curriculum has been streamlined – to allow more time for discipline-specific training, self-
directed career development/exploration and experiential learning. The program has following major
objectives: (1) To provide outstanding, interdisciplinary research training enriched by unique resources created
by UR's CFAR and CTSI; (2) To provide outstanding didactic and hands-on education in HIV/AIDS research.
This will be achieved by incorporating four major component – a required core didactic curriculum, required
program-specific group experiences; (3) optional elective courses, and experiences designed to encourage
student exploration and autonomy and (4) hands-on thesis research; (3) To enhance training outcomes via
structured mentoring. In this case the students will receive autonomy-supportive mentoring, which will be
further enhanced by supplementary `Peer Mentoring' and through an Alumni Mentoring Network that will
provide advice, guidance and informal mentoring on a one-on-one basis. To strengthen faculty mentoring
practices we will employ “mentor our mentors” program; and (4) To empower student autonomy, and to
encourage self-directed learnin...

## Key facts

- **NIH application ID:** 9920657
- **Project number:** 5T32AI049815-20
- **Recipient organization:** UNIVERSITY OF ROCHESTER
- **Principal Investigator:** Joseph E Wedekind
- **Activity code:** T32 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $193,559
- **Award type:** 5
- **Project period:** 2001-07-20 → 2022-06-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/9920657

## Citation

> US National Institutes of Health, RePORTER application 9920657, Training in HIV Replication and Pathogenesis (5T32AI049815-20). Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/grant/nih/9920657. Licensed CC0.

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