# Implementation Core

> **NIH NIH U54** · VANDERBILT UNIVERSITY MEDICAL CENTER · 2020 · $301,623

## Abstract

PROJECT SUMMARY – IMPLEMENTATION CORE 
 The benefits of precision medicine have yet to be fully realized, in part because effective implementation is 
impeded by numerous barriers. Barriers to the use of precision medicine are often magnified among racial and 
ethnic minority groups. In order for precision medicine discoveries to be effectively translated into practice, it 
will be critical to address these barriers and complexities through the science of implementation, which is the 
bridge between research and practice. The overall goal of the Implementation Core is to foster the adoption 
and dissemination of precision medicine initiatives for racial and ethnic minorities. Areas of emphasis will 
include genomic health literacy, using principles of community engagement to enhance adoption of precision 
medicine, and biomedical ethics. The Specific Aims are: 
 1. To identify barriers and facilitators to implementation and adoption of precision medicine 
 discoveries among racial and ethnic minorities. 
 2. To develop strategic approaches to speed the dissemination, diffusion and adoption of 
 evidence-based strategies developed through the Center. 
 3. To address ethical issues related to precision medicine among racial and ethnic minorities. 
 Given the general public's lack of familiarity with precision medicine, most of our activities will focus on 
working with the community to identify factors that may influence successful implementation of precision 
medicine and identifying, developing, and disseminating strategies to ensure practices are relevant, useful, 
attractive, and feasible for our target audiences. Specific work in this area will include a series of stakeholder 
surveys and focus groups to examine barriers and facilitators, including issues related to genomic health 
literacy, language, culture, trust, and concerns about privacy. From this, we will develop dissemination 
materials and other strategies to address barriers/facilitators, such as trust, and genomic health literacy. Other 
activities will target processes important in the later stages of implementation and attempt to work with the 
community on an ongoing basis to help them through barriers such as developing culturally informed 
implementation materials to enhance feasibility and fidelity of Center research projects and engaging partners 
that will make the program improvements sustainable over time.

## Key facts

- **NIH application ID:** 9921222
- **Project number:** 5U54MD010722-05
- **Recipient organization:** VANDERBILT UNIVERSITY MEDICAL CENTER
- **Principal Investigator:** SUNIL KRIPALANI
- **Activity code:** U54 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $301,623
- **Award type:** 5
- **Project period:** — → 2023-03-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/9921222

## Citation

> US National Institutes of Health, RePORTER application 9921222, Implementation Core (5U54MD010722-05). Retrieved via AI Analytics 2026-06-10 from https://api.ai-analytics.org/grant/nih/9921222. Licensed CC0.

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