# Administrative Core

> **NIH NIH P30** · LSU PENNINGTON BIOMEDICAL RESEARCH CTR · 2020 · $198,477

## Abstract

B. Abstract (Administrative Core)
The Pennington Biomedical (PBRC) Nutrition Obesity Research Center (NORC) was initially established
more than 9 years ago to facilitate and promote collaborative and multi-disciplinary interactions to foster new
research ideas and enhance the translation of basic nutritional research findings into the clinical arena and
ultimately into practical application. In agreement with the reviewers' feedback, we have now expanded from
our original theme of “nutritional programing” to emphasize the more general theme of “nutrition, obesity and
metabolic health through the lifespan”. Like most of the NIDDK NORCs, our research base is related to
the metabolic consequences of nutrition on health and diseases. We now plan to address big research
questions in obesity and nutrition from the basic science level, to clinical investigation and finally to the
population in a translational way. Our overall aim is to focus on the mechanisms involved in health and
disease, the study of treatment intervention and the implementation of preventive strategies. The long standing
tradition of nutrition and obesity research at PBRC provides an ideal academic environment to undertake
interdisciplinary efforts to investigate the environmental and molecular interactions underlying health and
disease. With our past 5 years extension of resources (faculty, clinical space, equipment, and support
personnel), and an established cadre of outstanding scientists, a Pennington NORC catalyzes novel nutrition
and obesity research around the targeted theme.
Besides an Administrative Core which provides the administrative infrastructure that will facilitate successful
completion of Aims for all Cores, the NORC encompasses 3 scientific cores.
 1) The “Human Phenotyping Core” aims to: provide a comprehensive suite of innovative energy balance
 and behavioral services in clinical and translational research studies; provide specialist expertise to
 members; administer a human tissue bio-repository and; expand our fMRI capabilities.
2) The “Animal Models and Phenotyping Core” provides the required animal models including conditional
 transgenic or knockout animals and state of the art phenotyping especially in energy balance studies.
3) The “Molecular Mechanisms Core” offers technologies to discover changes to the epigenome, and
measure altered gene expression (i) on the functional genomics and systems biology level by profiling
RNA expression, (ii) on the level of tissues and cells by quantitative bioimaging technology to detect
where gene expression is affected. A novel development is the analyses of gut microbiome using 16S
rRNA metagenomics sequencing.
Every year, the NORC also provides support for 2-4 Pilot & Feasibility grants and an Enrichment Program.
With an exceptional institutional support, an ideal academic environment and now collaboration with other
academic institutions in Louisiana, Pennington has established a strong base of obesity/nutrition res...

## Key facts

- **NIH application ID:** 9923626
- **Project number:** 5P30DK072476-15
- **Recipient organization:** LSU PENNINGTON BIOMEDICAL RESEARCH CTR
- **Principal Investigator:** Eric Ravussin
- **Activity code:** P30 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $198,477
- **Award type:** 5
- **Project period:** — → —

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/9923626

## Citation

> US National Institutes of Health, RePORTER application 9923626, Administrative Core (5P30DK072476-15). Retrieved via AI Analytics 2026-06-11 from https://api.ai-analytics.org/grant/nih/9923626. Licensed CC0.

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