# Infectious Disease/Basic Microbial Pathogenic Mechanisms

> **NIH NIH T32** · WASHINGTON UNIVERSITY · 2020 · $567,470

## Abstract

PROJECT ABSTRACT
This is an application to renew the Infectious Diseases/Basic Microbial Pathogenesis Training Grant
from Washington University. With the advent of generally available antibiotic therapy about 50 years
ago, many physicians and scientists predicted the end of infectious diseases as a major area of health
concern. Subsequent events have proven this prediction wrong, and the past decades have seen the
emergence of many newly identified infectious diseases, including Lyme Disease, erlichiosis, SARS,
West Nile encephalitis, chikungunya, MERS, ebola and HIV. The reemergence of old infectious
diseases, such as malaria and tuberculosis, in more virulent and more antibiotic resistant forms also
has increased public attention on the health problems posed by infectious diseases. It is rare that a
week goes by without some troubling headline concerning new infectious disease outbreaks. Thus, far
from gradual disappearance as a health concern, infectious diseases have emerged as being of
increasing importance to the health concerns of the nation. The emerging antibiotic resistance of
current pathogens and the rise of new disease agents have made clear the necessity of increased
fundamental scientific investigation into all aspects of infectious diseases. The purpose of the
Washington University Training Program in Infectious Diseases/Basic Microbial Pathogenesis is to help
fulfill this need by recruiting promising young investigators to this field and training them in outstanding
research programs with preeminent investigators who collaborate across multiple disciplines (or who
function in interdisciplinary teams) to perform infectious disease research. Our Training Program, which
has had NIH support for the past 35 years, integrates faculty from four departments: Medicine,
Pediatrics, Molecular Microbiology and Pathology & Immunology. The program provides training to
M.D., Ph.D., and M.D./Ph.D. postdoctoral fellows, and to Ph.D. and M.D./Ph.D. students, in disciplines
related to pathogenesis and host defense in Infectious Diseases. The laboratories of the program
preceptors use tools of molecular biology, biochemistry, genetics, genomics, immunology, cell biology
and translational medicine. Thus, the program trains young investigators to be able to answer the
important questions of microbial pathogenesis, from studies of basic biology through application to the
bedside.

## Key facts

- **NIH application ID:** 9924434
- **Project number:** 5T32AI007172-40
- **Recipient organization:** WASHINGTON UNIVERSITY
- **Principal Investigator:** Daniel E. Goldberg
- **Activity code:** T32 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $567,470
- **Award type:** 5
- **Project period:** 1980-09-15 → 2021-06-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/9924434

## Citation

> US National Institutes of Health, RePORTER application 9924434, Infectious Disease/Basic Microbial Pathogenic Mechanisms (5T32AI007172-40). Retrieved via AI Analytics 2026-05-25 from https://api.ai-analytics.org/grant/nih/9924434. Licensed CC0.

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