# HIV Vaccines

> **NIH NIH R13** · KEYSTONE SYMPOSIA · 2020 · $18,600

## Abstract

ABSTRACT
Support is requested for a Keystone Symposia conference entitled HIV Vaccines, organized by Drs.
Persephone Borrow, Georgia D. Tomaras and Rogier W. Sanders. The conference will be held in Keystone,
Colorado from March 22-26, 2020.
Development of effective prophylactic human immunodeficiency virus (HIV) vaccines are still urgently needed
to halt the spread of the HIV/AIDS pandemic. However, development of these vaccines has proven to be a
challenge that, despite intensive research efforts over the last 30 years, science has failed to surmount.
Nevertheless, the prospects for an effective HIV vaccine have recently been transformed by a series of
advances in science. These advances suggest that induction of broadly-reactive antibodies that confer
protection via neutralization and/or neutralization-independent mechanisms and elicitation of cytotoxic (CD8) T
cell responses can potentially eradicate the virus early after transmission and may ultimately prove to be
achievable goals for drug development. This conference will bring together interdisciplinary investigators
whose complementary expertise will synergize to inform HIV vaccine design and evaluation to discuss
progress and outstanding challenges in areas such as: 1) The design of immunogens and strategies for
optimization of germinal center responses to elicit HIV-1 broadly neutralizing antibodies; 2) Identifying
prospects for harnessing other antibody effector functions to confer protection; 3) Developing approaches for
eliciting rapidly-acting, efficacious HIV-specific CD8 T cell responses; and 4) How to use novel technologies,
animal model systems and small-scale clinical trials to inform vaccine development efforts. This conference is
being held jointly with HIV Pathogenesis and Cure. This pairing will provide an opportunity for interaction
between investigators working in these related areas, and for joint discussion of therapeutic vaccination
strategies.

## Key facts

- **NIH application ID:** 9925404
- **Project number:** 1R13AI150327-01
- **Recipient organization:** KEYSTONE SYMPOSIA
- **Principal Investigator:** Thale Cross Jarvis
- **Activity code:** R13 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $18,600
- **Award type:** 1
- **Project period:** 2020-02-01 → 2022-01-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/9925404

## Citation

> US National Institutes of Health, RePORTER application 9925404, HIV Vaccines (1R13AI150327-01). Retrieved via AI Analytics 2026-05-23 from https://api.ai-analytics.org/grant/nih/9925404. Licensed CC0.

---

*[NIH grants dataset](/datasets/nih-grants) · CC0 1.0*