# Imaging, Methodology and Statistics Core

> **NIH NIH P01** · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · 2020 · $417,801

## Abstract

IMS Core Summary/Abstract:
The IMS Core will continue to coordinate efficient and consistent utilization of
neuroimaging and non-neuroimaging measures and provide statistical support across projects and cores for
this program project grant (PPG), as it has done since 2005. The IMS Core provides methods and staff
support that is readily accessible to investigators and is a technical core for image data acquisition, processing,
analysis, and evaluation. The Core also provides data and database management support and is an integral
component of each project and is linked to all projects and Cores.
The IMS core will also continue to: 1) provide valid and standardized neuroimaging methods for PET and MR
data acquisition with timely analysis and evaluation; 2) provide data management that ensures timely and
secure database entry, storage, retrieval, quality control (QC) checks, and archiving; 3) provide statistical
consultation; and 4) serve as a methodology training and mentorship resource.
Aim 1. To acquire and manage neuroimaging (PET and MRI) and non-imaging data across the PPG
Aim 2. To provide robust structural and functional neuroimaging measures for primary (and exploratory) aims
Aim 3. To provide tools that can be used to determine temporal and spatial characteristics of neuroimaging
 measures across time and relative to non-imaging covariates and/or post-mortem correlates
Aim 4. To provide robust antemortem PET (PiB, [F-18]AV-1451) measures for postmortem correlations
Aim 5. To provide imaging and statistical consultation to investigators to achieve the project aims
Aim 6. To provide training to students and faculty in neuroimaging, statistics and clinical
The IMS Core will organize two weekly meetings: 1) IMS meetings with other PPG researchers to discuss
PET and MRI data acquisition, processing, analysis and general methodology issues and study progress; 2)
Biostatistics Imaging group meetings to discuss issues related to the statistical analyses across the 4 projects.
An annual IMS lecture series (September-July) will provide formal training on topics related to neuroimaging
acquisition and analyses, statistical approaches and clinical areas relevant to the PPG clinical goals.

## Key facts

- **NIH application ID:** 9927984
- **Project number:** 5P01AG025204-15
- **Recipient organization:** UNIVERSITY OF PITTSBURGH AT PITTSBURGH
- **Principal Investigator:** Julie C Price
- **Activity code:** P01 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $417,801
- **Award type:** 5
- **Project period:** — → 2022-04-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/9927984

## Citation

> US National Institutes of Health, RePORTER application 9927984, Imaging, Methodology and Statistics Core (5P01AG025204-15). Retrieved via AI Analytics 2026-05-28 from https://api.ai-analytics.org/grant/nih/9927984. Licensed CC0.

---

*[NIH grants dataset](/datasets/nih-grants) · CC0 1.0*