# HIV and Aging: From the Mitochondria to the Metropolis

> **NIH NIH R13** · EMORY UNIVERSITY · 2020 · $49,945

## Abstract

HIV and Aging: From the Mitochondria to the Metropolis
ABSTRACT
Building on the success of our first NIA-supported HIV and Aging conference held in October 2014, the primary
aims of this R13 application are to: a) Advance the state of the science on HIV and aging and speed translation
of findings to the community by conducting 3 conferences over a 5 year period; and b) Create and build a
pipeline of diverse multidisciplinary scientists who will conduct translational research focusing on the gaps in
knowledge and research related to HIV and Aging. The findings and recommendations from the Office of AIDS
Research Working Group on HIV and Aging (OAR WG) form the foundation and framework for our
conferences. Our intent is to attract and bring together experts, clinicians, early stage investigators, and
community leaders from the fields of both HIV and Aging. We expect these conferences to lead to the following
outcomes: a) increase knowledge in the field and provide a viable mechanism for translating basic and clinical
science findings to the community of persons living with HIV/AIDS (PLWH) (i. e, from the “mitochondria to the
metropolis”); b) Interdisciplinary collaborations focused on clinical and research gaps; c) Development of a
pipeline of new HIV and Aging researchers and development of research proposals related to the research
agenda outlined by the OAR WG and operationalized via the conferences; d) dissemination of conference
content to a broad range of professionals. The conferences will be planned by Executive and Scientific Boards
with substantial representation from the community and include content experts for planning the second and
third conferences. The Executive Board will be led by Co-PI’s who co-direct Emory’s CFAR Scientific Working
Group on HIV and Aging with strong collaboration by CFARs and Centers for Aging. All conferences will be
held in Atlanta, GA. The specific themes of the three conferences include: Functional Wellness (2017): A
person-centered, bio-behavioral approach to maximizing health and wellness that acknowledges and
addresses both internal (e.g., health behavior, individual responses to stress and illness) and external (e.g.,
environmental health) factors that impact aging. Aging and Special Populations (2019): The unique needs of
sub-groups of aging PLWH who require specialized interventions and treatment. They include racial/ethnic
minorities; women; MSM; transgender; veterans; substance users; those co-infected with hepatitis C; and
homeless or marginally housed. Population Determinants of Health (2021): The range of individual behavioral,
genetic and biological, and social determinants, including social/societal characteristics, physical environment,
and health services, that shape health and wellness of older PLWH. All three conferences and their
corresponding themes address critical knowledge gaps identified by the OAR WG. Each conference will weave
together basic and physiologic science, behavioral/psych...

## Key facts

- **NIH application ID:** 9930001
- **Project number:** 5R13AG047064-06
- **Recipient organization:** EMORY UNIVERSITY
- **Principal Investigator:** Marcia McDonnell Holstad
- **Activity code:** R13 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $49,945
- **Award type:** 5
- **Project period:** 2013-09-30 → 2022-04-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/9930001

## Citation

> US National Institutes of Health, RePORTER application 9930001, HIV and Aging: From the Mitochondria to the Metropolis (5R13AG047064-06). Retrieved via AI Analytics 2026-05-25 from https://api.ai-analytics.org/grant/nih/9930001. Licensed CC0.

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