# Translational Core

> **NIH NIH P01** · YALE UNIVERSITY · 2020 · $134,883

## Abstract

PROJECT SUMMARY/ABSTRACT 
The purpose of the Translational Core (Core D) is to provide access to human tissue, genetic material, clinical 
data, and statistical support to determine the clinical relevance of the biological questions being investigated in 
the projects of this Program Project Grant. Archived liver biopsies stored by the Department of Pathology plus 
the Yale Liver Center's patient registry and serum, DNA and tissue specimens will be available, which in total 
represents specimens and/or patient data from nearly 20,000 unique patients. The Core's Liver Pathologist 
and Research Coordinator will work with the Project Leaders to identify, retrieve and interpret relevant bio- 
specimens and handle necessary IRB protocols. The Core's statistician will work with the Project Leaders and 
Translational Core staff to address power analyses, sample sizes, and other relevant statistical considerations. 
This core will enable each Project Leader to relate their basic observations in cells and animal models to 
changes in expression and tissue localization of the corresponding genes and proteins of interest in patients 
under normal conditions and in specific liver disease states.

## Key facts

- **NIH application ID:** 9931207
- **Project number:** 5P01DK057751-20
- **Recipient organization:** YALE UNIVERSITY
- **Principal Investigator:** Kisha A Mitchell
- **Activity code:** P01 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $134,883
- **Award type:** 5
- **Project period:** — → 2022-04-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/9931207

## Citation

> US National Institutes of Health, RePORTER application 9931207, Translational Core (5P01DK057751-20). Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/grant/nih/9931207. Licensed CC0.

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