Antimicrobial and Biocompatible Endotracheal Tubes

NIH RePORTER · NIH · R44 · $786,197 · view on reporter.nih.gov ↗

Abstract

Ventilator-associated pneumonia (VAP) occurs 48–72 hours (or more) following endotracheal intubation and accounts for half of all cases of hospital-acquired pneumonia. CDC reports and many clinical studies point to a critical need for preventing ventilator associated infections rather than fighting an often losing battle against acquired infection. Responding to this unmet need, WynnVision LLC, “WV” will leverage strong preliminary results for antimicrobial-but-cytocompatible (ABC) nano- overcoats on as-manufactured intubation products to develop a new technology for eliminating or greatly reducing VAP/VAE. The WV approach, protected by a recent patent application, will involve multidisciplinary activities and third party testing to facilitate approaching FDA for approval.

Key facts

NIH application ID
9931267
Project number
5R44HL142391-03
Recipient
WYNNVISION, LLC
Principal Investigator
XUEJUN WEN
Activity code
R44
Funding institute
NIH
Fiscal year
2020
Award amount
$786,197
Award type
5
Project period
2018-08-15 → 2023-04-30