# Coronary Heart Disease in Black Women: The Role of Adverse Pregnancy Outcomes

> **NIH NIH K01** · BOSTON UNIVERSITY MEDICAL CAMPUS · 2020 · $122,445

## Abstract

PROJECT SUMMARY
This proposed five-year career development period will be used for research and training activities that will give
Dr. Samantha Parker the skills and experience necessary to become an independent investigator. Dr. Parker’s
long-term career goal is to apply the theory and analytical tools of life course epidemiology to the study of
adverse pregnancy outcomes and risk of maternal cardiovascular disease. Building on a strong background in
reproductive epidemiology and epidemiologic methods, Dr. Parker has proposed content area training in
cardiovascular epidemiology and applied skills of statistical methods for life course epidemiology, including
mediation analysis. She has also included training regarding social determinants of health to learn about
individual-level and neighborhood-level social determinants as they relate to adverse pregnancy outcomes and
cardiovascular disease. The training plan involves formal coursework, symposia and workshops, and didactic
experiences and the establishment of a mentoring panel representing expertise in each training domain. The
research aims are to investigate the association between adverse pregnancy outcomes and maternal risk of
coronary heart disease (CHD) in the Black Women’s Health Study, the largest cohort study of black women in
the United States. An accumulating body of evidence on this topic exists in predominantly white populations,
but there is a dearth of evidence among black populations, despite persistent racial disparities in CHD
morbidity and mortality. The aims will also address mediation by clinical risk factors for CHD, including chronic
hypertension and diabetes, and modification by life course measures of individual-level and neighborhood-level
social determinants of health.

## Key facts

- **NIH application ID:** 9931285
- **Project number:** 5K01HL133600-05
- **Recipient organization:** BOSTON UNIVERSITY MEDICAL CAMPUS
- **Principal Investigator:** Samantha Parker Kelleher
- **Activity code:** K01 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $122,445
- **Award type:** 5
- **Project period:** 2016-08-15 → 2021-11-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/9931285

## Citation

> US National Institutes of Health, RePORTER application 9931285, Coronary Heart Disease in Black Women: The Role of Adverse Pregnancy Outcomes (5K01HL133600-05). Retrieved via AI Analytics 2026-07-16 from https://api.ai-analytics.org/grant/nih/9931285. Licensed CC0.

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