# Effects of Ambulance, Transport Distance, and Hospital Destination on Health Outcomes of Out-of-Hospital Medical Emergencies

> **NIH AHRQ R01** · UNIVERSITY OF CHICAGO · 2020 · $377,342

## Abstract

Pre-hospital care plays a crucial role in determining health outcomes after trauma and out-of-hospital
complications of other leading causes of death, such as stroke and heart disease. Yet, it has largely been
neglected by the scientific community, leaving assumptions rather than evidence to guide policy decisions on
the ambulance type and hospital destination that would optimize a patient’s health outcomes. In previous work,
our team compared two competing strategies for delivering emergency ambulance care, advanced life support
(ALS) and basic life support (BLS), and found that ALS, which is much more common in the United States, may
be less successful in keeping patients alive and as well as possible. In this work, we studied several out-of-
hospital medical emergencies using quasi-experimental research methods and a large national sample of
Medicare claims from 2006-2011. In our first aim of the proposed work, we will extend this analysis to the under
65 adult Medicaid population, which is particularly important to do for major trauma as younger people sustain
different patterns of injury than older adults. In addition to major trauma, we will also study out-of-hospital cardiac
arrest, stroke, respiratory failure, and acute myocardial infarction, all of which are time sensitive conditions
requiring prompt medical care. The next aim will build upon this and our previous work and analyze choice of
hospital destination for ALS and BLS patients. To date, regionalization studies that evaluate outcomes of out-of-
hospital medical emergencies at specialty hospitals like trauma centers rarely account for the amount of time
spent in pre-hospital care, which is influenced by whether that care was provided by ALS or BLS, or adequately
study the trade-off between minimizing travel distance and optimizing hospital characteristics. We will improve
upon the existing literature using Medicare and Medicaid claims, regression analysis, and causal inference
methods to study the associations and causal relationships between these key factors and survival. To describe
the broad implications of our findings, in our third aim we will quantify the potential benefits at the national level
of optimizing individual pre-hospital care decisions based on existing resources using a microsimulation model.
Finally, for longer-term policymaking, we will assess how shifts in ambulance resources and hospital locations
in four states might affect population health outcomes for out-of-hospital medical emergencies. The proposed
work will advance safety and quality research for the pre-hospital care system and hospital regionalization and
will fill critical gaps in the scientific literature. We expect to provide specific, evidence-based insights that
policymakers can use to substantially improve pre-hospital and hospital care for out-of-hospital medical
emergencies. Importantly, our use of Medicaid claims and focus on trauma care will be particularly relevant to
inner-city, low-inc...

## Key facts

- **NIH application ID:** 9933037
- **Project number:** 5R01HS025720-04
- **Recipient organization:** UNIVERSITY OF CHICAGO
- **Principal Investigator:** Prachi Sanghavi
- **Activity code:** R01 (R01, R21, SBIR, etc.)
- **Funding institute:** AHRQ
- **Fiscal year:** 2020
- **Award amount:** $377,342
- **Award type:** 5
- **Project period:** 2017-09-08 → 2022-12-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/9933037

## Citation

> US National Institutes of Health, RePORTER application 9933037, Effects of Ambulance, Transport Distance, and Hospital Destination on Health Outcomes of Out-of-Hospital Medical Emergencies (5R01HS025720-04). Retrieved via AI Analytics 2026-05-23 from https://api.ai-analytics.org/grant/nih/9933037. Licensed CC0.

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