# Hormone Assay and Analytical Services Core

> **NIH NIH P30** · VANDERBILT UNIVERSITY MEDICAL CENTER · 2020 · $229,399

## Abstract

Hormone Assay & Analytical Services Core (HAASC): Project Summary/Abstract
The purpose of the Hormone Assay & Analytical Services Core (HAASC) is to provide to investigators assays
to measure hormones, cytokines, amino acids (Specific Activity & concentrations), lipids/lipoproteins,
nucleotides and markers of oxidant stress in biologic fluids and tissue samples, and more recently glucose
(enrichment and isotopomer distribution) in plasma and tissue samples. The services provided by the HAASC
and its two subcores (Oxidative Stress Subcore and Lipid Subcore) require unique instrumentation and involve
rigorous standardization of procedures. It is neither practical nor economically reasonable to establish these
assays in individual laboratories. The consolidation of services into one Core laboratory provides investigators
with efficient, high quality, low cost analyses. All services are tailored to meet the needs of the specific
investigator in that the exact protocol followed may differ depending on the analysis desired by the investigator
and the sample volume to be analyzed. Through training and education, investigators become more aware of
the various services offered and how these services might address specific areas of interest. Finally, an
important function of the Core is method development, which not only enhances the spectrum of services
offered but ultimately also increases efficiency by providing researchers with the opportunity to expand their
research programs. The core provides space, equipment, and personnel for sample analysis. Investigators pay
a fee-for-service that covers the cost of reagents, supplies, pro-rated service contracts for equipment, and a
percentage of personnel salary. The Core also serves as a valuable resource for all investigators without ready
access to wet-lab research space and personnel. Core services utilize modern instrumentation run by
experienced research assistants in a consistent, quality-controlled environment. This Core works closely with
another VDRTC Core, the Metabolic Physiology Shared Resource, to develop standard operating procedures
to facilitate translation of this technology to VDRTC investigators performing in vivo and in vitro studies. Those
investigators rely on the Core and Subcore directors and their staff for advice on how to collect and process
samples collected during in vivo studies. The Hormone Assay and Analytical Services Core provides essential
services to VDRTC investigators that allow them to perform important and innovative research. The HAASC
has demonstrated its ability to develop and modify assays to meet the evolving needs of VDRTC investigators.

## Key facts

- **NIH application ID:** 9933893
- **Project number:** 5P30DK020593-43
- **Recipient organization:** VANDERBILT UNIVERSITY MEDICAL CENTER
- **Principal Investigator:** OWEN P MCGUINNESS
- **Activity code:** P30 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $229,399
- **Award type:** 5
- **Project period:** — → —

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/9933893

## Citation

> US National Institutes of Health, RePORTER application 9933893, Hormone Assay and Analytical Services Core (5P30DK020593-43). Retrieved via AI Analytics 2026-05-22 from https://api.ai-analytics.org/grant/nih/9933893. Licensed CC0.

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