# Core B: Infectious Disease Assay Development

> **NIH NIH P20** · UNIVERSITY OF KANSAS LAWRENCE · 2020 · $171,019

## Abstract

SUMMARY 
The overall goal of the Infectious Disease Assay Development (IDAD) Core is provide expertise, facilities, 
services, and training in the area of HTS assay design, development, validation, small and large-scale 
screening for organism (cell) based or biochemical infectious disease targets. Assay development and 
performing high-throughput screening for infectious disease targets can be very similar to other biological and 
disease targets; however, there are often specific biological hazards associated with infectious disease targets 
that can require special consideration and conditions. This core will build upon current assets and expand the 
current capabilities by providing enabling expertise and dedicated attention of a core director and a technician 
to the community of infectious disease scientists and their biologically and disease relevant targets. Core staff 
will facilitate design, development, validation of assays suitable for automated high-throughput chemical 
screening. They will also facilitate small or large scale screening of compounds (at KU or from external 
sources). The expected outcomes of this core and associated efforts are well developed and validated assays 
suitable for automated large-scale screening that can be performed internally or externally. Hits generated 
through successful assay development and limited or large scale screening efforts will be directed into Core C 
and Core D to identify lead compounds for use as molecular probes and pre-therapeutics for infectious 
diseases. The expertise and resources will also enable investigators to develop competitive proposals in 
response to NIH funding opportunities.

## Key facts

- **NIH application ID:** 9935090
- **Project number:** 5P20GM113117-05
- **Recipient organization:** UNIVERSITY OF KANSAS LAWRENCE
- **Principal Investigator:** P Scott Hefty
- **Activity code:** P20 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $171,019
- **Award type:** 5
- **Project period:** 2020-05-01 → 2021-07-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/9935090

## Citation

> US National Institutes of Health, RePORTER application 9935090, Core B: Infectious Disease Assay Development (5P20GM113117-05). Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/grant/nih/9935090. Licensed CC0.

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