# MEDIC - MicroED Imaging Center - Admin Core

> **NIH NIH P41** · UNIVERSITY OF CALIFORNIA LOS ANGELES · 2020 · $1,327,343

## Abstract

ADMINISTRATION AND MANAGEMENT
SUMMARY
The Administrative Core (AC) will provide an organizational framework for the proposed multi-investigator
project, the MEDIC – MicroED Imaging Center at UCLA. The AC will be led by the two PIs, Drs. Tamir Gonen
and Pawel Penczek. The joint directorship of the MEDIC center will ensure efficient functioning of the Resource
uninterrupted by other responsibilities of the PIs. The activities of this Core will include synchronization of the
research and technology development of all groups, the maintenance of communications with and between
Driving Biological Projects, the resolution of budgetary issues, organization of monthly meetings for an Internal
Advisory Committee, a yearly meeting of an External Advisory Meeting, and up to two training and dissemination
workshops per year. It will also be responsible for the preparation of the yearly Progress Report and will maintain
and update the Resource Sharing facility. The center will benefit from Dr. Gonen having extensive experience in
managing cryoEM resources and multi-user facility projects. Dr. Gonen established and directed several cryoEM
facilities around the USA in the last 15 years, including the most prolific cryoEM user facility at the Janelia
Research Campus of HHMI which was the first synchrotron-like facility for cryoEM in the world. Dr. Penczek has
20 years of successful NIH-supported research including participation in multi-PI program project and joined PI
grants. In addition, for 12 years Dr. Penczek served as a Director of the UTH Structural Biology Imaging Center,
a multi-user facility supporting structural biology research at UT Medical Center, including NMR, X-ray
crystallography, and cryo-EM and operating under an independent budget. Under his leadership the facility grew,
culminating in the successful acquisition of a UT-funded Krios TEM in 2017. Since 2017 Dr. Penczek serves as
a co-director of the UT Center. Together, Drs. Gonen and Penczek will formulate an Internal Advisory Committee
comprised of elite members of the Technology Research and Development projects (TRDs) and select key
personnel. This committee will establish and ensure optimal operating procedures for MEDIC, access
procedures and criteria for determining eligible projects. It will be also responsible for determination and the
format of technology dissemination workshops and, if necessary, for reallocation of funds between TRD projects.
Of utmost importance is the establishment of the External Advisory Committee. The role of this Committee will
be to advise on the overall scientific direction of the project, advise on dissemination efforts and community
engagement, help to maintain its focus and to stay devoted and faithful to the original mission of MEDIC. The
Administrative Core will organize a yearly one-day meeting of the External Advisory Committee and its members
will be expected to prepare a report that will be shared with all PIs and key personnel of the Project and w...

## Key facts

- **NIH application ID:** 9935722
- **Project number:** 1P41GM136508-01
- **Recipient organization:** UNIVERSITY OF CALIFORNIA LOS ANGELES
- **Principal Investigator:** Tamir Gonen
- **Activity code:** P41 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $1,327,343
- **Award type:** 1
- **Project period:** — → —

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/9935722

## Citation

> US National Institutes of Health, RePORTER application 9935722, MEDIC - MicroED Imaging Center - Admin Core (1P41GM136508-01). Retrieved via AI Analytics 2026-05-22 from https://api.ai-analytics.org/grant/nih/9935722. Licensed CC0.

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