# Epidemiology and Genetics Core

> **NIH NIH P30** · BOSTON MEDICAL CENTER · 2020 · $119,995

## Abstract

The Epidemiology and Genetics (E&G) Core, under the direction of Dr. Frank Hu, provides members with
access to data and biological specimen banks from large prospective cohort studies including the Nurses'
Health Studies (based at Brigham Women's Hospital), the Health Professionals Health Study (based at the
Harvard School of Public Health), the Framingham Heart Study (based at Boston University), Project Viva
(based at Harvard Medical School), Boston Puerto Rican Health Study (based at Northeastern University and
Tufts University). The Core also provides consultation services in design and analysis for epidemiologic
studies with a focus on obesity and nutrition (as exposure or outcome) and for epidemiologic studies aimed at
understanding the biologic basis of obesity and related phenotypes through the use of genetics and –omics
technologies. The resources offered by the core have been central to the contributions of large GWAS studies
including the GIANT consortium (based at Broad Institute and Children's Hospital) and CHARGE consortium
(based at MGH), and fosters bidirectional cross-talk between basic and population scientists in the analysis of
candidate genes for obesity and altered nutrient metabolism and on the translation of findings in animal models
to human populations. In the last 4-year cycle (2012-2016) services provided by the core resulted in the
publication of 170 manuscripts –an increase from 124 in the previous 5-year competitive renewal cycle (2007-
2012)– including 13 manuscripts published in high impact medical journals (NEJM, JAMA, Lancet, BMJ). In
this competitive renewal we propose to further expand data access to include cohorts where hypotheses
regarding intergenerational effects of parental exposures on offspring obesity and related phenotypes can be
tested, as well as expanded access to and analytical support for projects involving metabolomics and gut
microbiome data from the prospective cohorts available through the core.

## Key facts

- **NIH application ID:** 9936248
- **Project number:** 5P30DK046200-28
- **Recipient organization:** BOSTON MEDICAL CENTER
- **Principal Investigator:** Frank B Hu
- **Activity code:** P30 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $119,995
- **Award type:** 5
- **Project period:** — → —

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/9936248

## Citation

> US National Institutes of Health, RePORTER application 9936248, Epidemiology and Genetics Core (5P30DK046200-28). Retrieved via AI Analytics 2026-05-22 from https://api.ai-analytics.org/grant/nih/9936248. Licensed CC0.

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