# Core A: Administrative Core

> **NIH NIH P01** · UNIVERSITY OF CALIFORNIA-IRVINE · 2020 · $57,570

## Abstract

CORE A: ADMINISTRATIVE CORE
PROJECT SUMMARY/ABSTRACT
This Program Project, “From Structure to Therapy: The TRiC Chaperonin Network in Huntington's Disease” is
focused on understanding the impact of modulating the TRiC chaperonin system on HD pathogenesis and
developing effective TRiC based therapeutic strategies and reagents to alleviate the pathological impact of
mutant huntingtin. The Administrative Core oversees the activities of the Program and provides infrastructure
support for the investigators to facilitate achieving the proposed goals of the Program. The Core will provide
support for oversight and governance, management and operations, as well as reporting and compliance
needs of all three projects. The Administrative Core will also monitor and oversee access to the shared
resource Repository core of the Program Project and establish a password protected interactive website for
real-time data sharing between Program investigators. The Administrative Core will promote the multi-
disciplinary and collaborative approach between the Projects by organizing bi-monthly conference calls and
quarterly face-to-face meetings. The Core will also assemble an External Advisory Committee to review
research progress and provide guidance for the Program Project and organize annual meetings with the
Program Project investigators. The Administrative Core will coordinate the meetings and facilitate an
environment to keep the program synergistic, productive and innovative. Finally, the Administrative Core will
coordinate material transfer agreements, oversee animal use protocols, facilitate travel for lab members
between Project sites and manage the financial budgets of the Cores and Projects.

## Key facts

- **NIH application ID:** 9936259
- **Project number:** 5P01NS092525-05
- **Recipient organization:** UNIVERSITY OF CALIFORNIA-IRVINE
- **Principal Investigator:** Leslie Michels Thompson
- **Activity code:** P01 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $57,570
- **Award type:** 5
- **Project period:** — → 2022-03-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/9936259

## Citation

> US National Institutes of Health, RePORTER application 9936259, Core A: Administrative Core (5P01NS092525-05). Retrieved via AI Analytics 2026-05-23 from https://api.ai-analytics.org/grant/nih/9936259. Licensed CC0.

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