# Core B: Repository Core

> **NIH NIH P01** · UNIVERSITY OF CALIFORNIA-IRVINE · 2020 · $37,479

## Abstract

CORE B: REPOSITORY CORE
PROJECT SUMMARY/ABSTRACT
In order to facilitate the goal of utilizing innovative molecular, cellular and animal model systems to examine
the interactions between mHTT and the TRiC network and to examine TRiC reagent modulations impact on
HD pathology, we will establish a repository core. Repositories are a critical resource for multi-researcher
initiated studies and have been established for NIH programs examining neurodegenerative diseases and
disorders. In general, repositories store and catalogue various reagents, protocols and other critical data with
the overall intention aimed at rapidly facilitating sharing resources for the development of new therapies.
Establishing a repository core for the work in the described proposal is a vital part of the Program Project Grant
to support the project goals. The Repository Core will support research throughout the projects by facilitating
production of standardized high quality peptide, vector, cell and tissue reagents, archiving of reagents and
protocols and distribution to project sites. Specific aims are to; 1) Establish a physical core for deposition of
TRiC and HTT reagents and a Program specific network, 2) Coordinate utilization of the Core

## Key facts

- **NIH application ID:** 9936260
- **Project number:** 5P01NS092525-05
- **Recipient organization:** UNIVERSITY OF CALIFORNIA-IRVINE
- **Principal Investigator:** JACK C REIDLING
- **Activity code:** P01 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $37,479
- **Award type:** 5
- **Project period:** — → 2022-03-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/9936260

## Citation

> US National Institutes of Health, RePORTER application 9936260, Core B: Repository Core (5P01NS092525-05). Retrieved via AI Analytics 2026-05-23 from https://api.ai-analytics.org/grant/nih/9936260. Licensed CC0.

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