# Cell Immunology and Metabolism Core (CIMC)

> **NIH NIH P20** · LSU HEALTH SCIENCES CENTER · 2020 · $22,799

## Abstract

ABSTRACT
The Cellular Immunology and Metabolism Core (CIMC) of the LSU Cancer Center provides cutting edge flow
cytometry, immunology and metabolism technologies LSUHSC investigators including COBRE PJI's, and to
other users in our region. The CIMC laboratory now provides comprehensive analytic flow cytometry, high-
speed cell sorting services, functional assays including antigen-specific and mitogen-induced cell proliferation,
cytokine production, cell death and survival, cell mediated cytotoxicity, and effector T cell frequency. The CIMC
also acquired and developed the infrastructure and expertise to study cellular metabolism, including oxygen
consumption and acidification rates, mitochondrial function; and the detection of immune mediators through
multiplex approaches. Therefore, state-of-the-art services of the CIMC are very well suited to support the
needs of PJIs of the new Phase I COBRE application ”Center for translational Viral Oncology” (CTVO). This
will be done by fully utilizing present services and resources, and by expending their expertise to identify new
biomarkers for virus-induced cancer, evaluation of cell growth and cell death responses associated with the
expression of viral oncoproteins and anticancer treatment. In addition, innovative approaches, which are
continuously implemented by the CIMC personnel will allow PJIs and their mentors to develop new
experimental strategies explaining virus-induced changes at the levels of tumor cell signaling, epigenetic
regulation and tumor cell energy metabolism, thereby increasing their chances for high impact publications and
federal and foundation-related funding. These advanced technologies have positioned the CIMC as the leading
laboratory in cancer and immunology in the region, which has resulted in an increased number of users,
including PJIs of the CTVO, and its integration as a core laboratory at the LSUHSC School of Medicine and the
LSU-Cancer Center.
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## Key facts

- **NIH application ID:** 9937780
- **Project number:** 5P20GM121288-04
- **Recipient organization:** LSU HEALTH SCIENCES CENTER
- **Principal Investigator:** AUGUSTO C. OCHOA
- **Activity code:** P20 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $22,799
- **Award type:** 5
- **Project period:** — → —

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/9937780

## Citation

> US National Institutes of Health, RePORTER application 9937780, Cell Immunology and Metabolism Core (CIMC) (5P20GM121288-04). Retrieved via AI Analytics 2026-05-23 from https://api.ai-analytics.org/grant/nih/9937780. Licensed CC0.

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