# Institutional Career Development Core

> **NIH NIH KL2** · ROCKEFELLER UNIVERSITY · 2020 · $857,275

## Abstract

The overarching goal of our Institutional Career Development Core is to prepare our trainees to be
successful translational investigators who improve human health.
Specific aims:
 1. To train physician scientists and doctoral level health professional as outstanding translational
 investigators in a 3 year mentored KL2 Clinical Scholars Master's degree program that includes: a)
 leadership of a human subjects protocol from conception to conclusion, and b) a didactic curriculum to
 help the Scholar master the competencies to function as an independent translational investigator,
 2. To introduce new educational programs to maximize Scholars' ability to benefit from emerging new
 technology and resources, including ones focused on providing competencies in: a) Engaging
 communities to insure that patients' and communities' priorities are in incorporated into all phases of
 protocol development and research conduct b) Developing ontology-driven human phenotyping, c)
 Querying Big Data Electronic Health Record warehouses to test hypotheses across the translational
 spectrum, and d) Rapidly and efficiently moving “From Discovery to Health-Enhancing Products.”
To accomplish these specific aims we developed a 3 year Master's degree KL2 Clinical Scholars Program in
which Scholars design, conduct, analyze, and disseminate the results of a human subjects protocol under the
guidance of a distinguished senior scientific mentor. This experiential core component is complemented: by a
didactic curriculum including tutorials in Clinical and Translational Science, Biostatistics, Bioinformatics, and
Epidemiology; a weekly Clinical Research Seminar by outstanding translational investigators; a private weekly
meeting with the seminar speaker; team science training; a graduate level scientific course; Humanities and
Translational Science special events; and training in the Responsible Conduct of Research. To maintain the
optimal size of ~15 trainees we complement the Scholars supported by the KL2 program with Scholars
supported by University resources. In the upcoming award period we will build on this program by adding new
components to strengthen the ability of the Scholars to: engage communities as full partners throughout the
entire protocol cycle, from development to dissemination and implementation; develop phenotyping
instruments that are backed by ontologies to enhance genotype-phenotype analyses; query large databases of
Electronic Health Records to test scientific hypotheses; and develop their laboratory discoveries into products
that improve human health. We will collect detailed metrics on each component of the program to drive
improvements and we will track the future progress of the graduates of the program with the on-line Graduate
Tracking Survey System we developed, which has been adopted by more than 20 other CTSA hubs.

## Key facts

- **NIH application ID:** 9937862
- **Project number:** 5KL2TR001865-05
- **Recipient organization:** ROCKEFELLER UNIVERSITY
- **Principal Investigator:** Sarah Jane Schlesinger
- **Activity code:** KL2 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $857,275
- **Award type:** 5
- **Project period:** 2016-07-05 → 2021-05-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/9937862

## Citation

> US National Institutes of Health, RePORTER application 9937862, Institutional Career Development Core (5KL2TR001865-05). Retrieved via AI Analytics 2026-05-23 from https://api.ai-analytics.org/grant/nih/9937862. Licensed CC0.

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