# 5-Laser Cytek Aurora Spectral Flow Cytometer

> **NIH NIH S10** · OKLAHOMA MEDICAL RESEARCH FOUNDATION · 2020 · $316,575

## Abstract

Abstract
The Oklahoma Medical Research Foundation requests funds for the purchase of a Cytek Aurora spectral flow
cytometer with five lasers (355 nm, 405 nm, 488 nm, 561 nm, and 640 nm). There are two reasons for our
request. First, our aging four-laser LSR II is increasingly unreliable, and a service contract will not be available
from the manufacturer after 2020. This instrument needs to be replaced. Second, many of our investigators
need higher content flow cytometry than can be carried out with a four-laser instrument. Some of our scientists
are doing detailed immunophenotyping of rare cell populations that depends upon a staining cocktail of more
than 24 monoclonal antibodies. Other investigators are characterizing leukocytes from tissue samples where
the numbers of cells are so low that all the analyses must be done with data from a single antibody cocktail. A
new 5-laser flow cytometer will increase the rigor, reproducibility and significance of our research and provide
our researchers with much needed flexibility when designing their experiments. Some of our scientists are
conducting basic biomedical research to understand how the immune system develops and fights infections.
Others are studying the causes and potential treatments for important human diseases including, multiple
sclerosis, age-related macular degeneration, autoimmune uveitis, Sjögren's Syndrome, systemic lupus
erythematosus, neuromyelitis optica, and sepsis. We anticipate that a new Aurora spectral flow cytometer from
Cytek will advance our research for at least the next decade.

## Key facts

- **NIH application ID:** 9938108
- **Project number:** 1S10OD028479-01
- **Recipient organization:** OKLAHOMA MEDICAL RESEARCH FOUNDATION
- **Principal Investigator:** Linda F Thompson
- **Activity code:** S10 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $316,575
- **Award type:** 1
- **Project period:** 2020-07-15 → 2021-07-14

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/9938108

## Citation

> US National Institutes of Health, RePORTER application 9938108, 5-Laser Cytek Aurora Spectral Flow Cytometer (1S10OD028479-01). Retrieved via AI Analytics 2026-05-28 from https://api.ai-analytics.org/grant/nih/9938108. Licensed CC0.

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